Contact Us
Find A Doctor

Stevens-Johnson Syndrome

What is Stevens-Johnson syndrome?

Stevens-Johnson syndrome is a rare, serious disorder of the skin and mucous membranes. It usually involves an idiosyncratic reaction to a medication or an infection. Often, it begins with flu-like symptoms, followed by a painful red or purplish rash that spreads and blisters. The top layer of the affected skin then dies, sheds and heals. All ages may be affected, and both sexes are equally susceptible. Stevens-Johnson syndrome has a 5%–15% mortality rate. Ocular involvement, which occurs in as many as half of patients, varies from mild  conjunctivitis to severe perforating corneal ulcers. Blindness occasionally occurs in patients with severe late-phase corneal complications, such as chronic corneal ulceration, vascularization, and perforation.

How is the condition treated?

Stevens-Johnson syndrome is a medical emergency that usually requires hospitalization. The first and most important step in treatment is to discontinue any medications that may be causing the condition. Supportive care you’re likely to receive while hospitalized includes fluid replacement and nutritional. Wound care is also essential. Your health care team may gently remove any dead skin and place petroleum jelly (Vaseline) or a medicated dressing over the affected areas. Early intervention is important in preventing ocular complications from Stevens-Johnson syndrome. Ocular lubrication with artificial tears and ointments (preferably preservative-free) should be applied regularly. All Stevens-Johnson syndrome patients need emergent consultation with an ophthalmologist at the time of diagnosis. 

Contact Us

Eye Faculty PracticeTel: 212-979-4500

Address310 E. 14th Street
South Building, 3rd Floor
New York, NY 10003

Eye ClinicTel: 212-979-4192

Address310 E. 14th Street
South Building, 1st Floor
New York, NY 10003

Tribeca OfficeTel: 212-966-3901

Address77 Worth StreetNew York, NY 10013

Columbus CircleTel: 212-957-6933

Address200 West 57th Street, Suite 1410New York, NY 10019

Upper East SideTel: 212-731-3355

Address234 East 85th StreetNew York, NY 10028

Ophthalmology FPATel: 212-241-0939

Address17 East 102nd StreetNew York, NY 10029

Midwood OfficeTel: 718-375-6933

Address1630 East 15th Street
Second Floor (Suite 203)
Brooklyn, NY 11229

Williamsburg OfficeTel: 718-384-6933

Address101 Broadway, Suite 201Brooklyn, NY 11249

Mineola OfficeTel: 516-408-4900

Address200 Old Country Road
Suite 125
Mineola, NY 11501

Westchester OfficeTel: 914-934-5280

Address90 S Ridge StreetRye Brook, NY 10573

View all locations

Find a Doctor

by Specialty by Name
Request a Referral