The Department of Ophthalmology maintains a strong commitment to medical research, which contributes to advances in ophthalmology and related areas of medicine through involvement in clinical investigations. Such research seeks to conquer eye disease, prevent blindness, and restore vision.

Why Should I Participate in a Clinical Trial?

Participation in clinical trials helps researchers uncover better ways to prevent, diagnose, treat, and understand diseases of the eye. In addition, clinical trials provide access to treatments which are otherwise unavailable.The information gained from clinical trials helps other people facing similar conditions.

Cornea, External Disease and Refractive Surgery

• A Double-Masked, Placebo-Controlled, Randomized, Phase II Clinical Trial To Assess The Efficacy Of SCH1 In The Treatment Of Acute Infectious Conjunctivitis
• Zoster Eye Disease Study

Glaucoma

• Continuous Wave Transscleral Cyclophotocoagulation and Micropulse Transscleral Cyclophotocoagulation: Efficacy and Effects on Corneal Endothelial Cell Count
• Gaze-Evoked Intraocular Pressure Change in Glaucoma
• Macular Vessel Density and Foveal Avascular Zone Changes in Exfoliation Glaucoma vs Primary Open Angle Glaucoma vs Exfoliation Syndrome: An Optical Coherence Tomography Angiography Study
• Nailfold Video Capillaroscopy as a Marker of Microvascular Changes in Patients with Primary Open Angle and Exfoliative Glaucoma
• Protocol for the Collection of Blood and Surgical Specimens from Patients With and Without Glaucoma
• Sensitivity and Specificity of the NOVA-VEP (FP) Fixed Protocol for Glaucoma Diagnosis

Retina

• IIT Age-related Macular Degeneration (AMD) and Cardiovascular Disease
• LUMINA Phase III Study Assessing the Efficacy and Safety of Intravitreal Injections of 440 ug DE-109 Sirolimus for the Treatment of Active, Non-Infectious Uveitis of the Posterior Segment of the Eye
• A Snapshot Adaptive Optics and Hyperspectral Autofluorescence Fundus Camera for Age-Related Macular Degeneration (AMD)
• Study to Assess the Efficacy, Safety, and Tolerability of Intravitreal Aflibercept Compared to Laser Photocoagulation in Patients With Retinopathy of Prematurity (BUTTERFLEYE)
• Study of Photobiomodulation to Treat Dry Age-Related Macular Degeneration (LIGHTSITE III)
• Study to Compare the Efficacy and Safety of Intravitreal APL-2 Therapy With Sham Injections in Patients With Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration (AMD)
• Telemedicine in Age-Related Macular Degeneration (AMD)

Office of Research Services

Research conducted by Icahn School of Medicine at Mount Sinai faculty, at the New York Eye and Ear Infirmary of Mount Sinai, is subject to Mount Sinai’s ethical and legal requirements for the conduct and oversight of human research. The Office of Research Services (ORS) serves as a central resource for the Mount Sinai Health System research community, and oversight of human subjects research is provided by the Program for the Protection of Human Subjects (PPHS).