New York Eye and Ear Infirmary
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Since its founding in 1820, the mission of New York Eye and Ear Infirmary of Mount Sinai (NYEE) has been for excellence in patient care for eye disease as well as education of eye care providers. To maintain excellence, research must be an integral part of this mission.

Researchers at New York Eye and Ear Infirmary were among the first to use the laser in treating retinal diseases. Today, the Department of Ophthalmology maintains a strong commitment to medical research, which contribute to advances in Ophthalmology and related areas of medicine.

Research of medical practitioners is facilitated by a staff of research scientists, neuro-ophthalmolgists, pathologists, and electrophysiologists, who likewise conduct independent research in their respective areas.

New York Eye and Ear Infirmary continues to be involved in many clinical and translational research projects. This site makes information about these trials available to all. The active protocols have information about:

  • the issue being studied and goal for the research
  • inclusion and exclusion criteria
  • contact person
  • other pertinent information

Find current clinical trials in Ophthalmology

For results of previous studies, go to www.clinicaltrials.gov

Glaucoma

Study/Title

Principal Investigator

NEW! Primary Tube Versus Trabeculectomy

Paul Sidoti, MD

Refractory Glaucoma

NEW! A Prospective, Multicenter Clinical Trial Designed to Evaluate the Safety and Performance of the AqueSys XEN45 Glaucoma Implant in Subjects with Refractory Glaucoma

Joseph Panarelli, MD

Glaucoma Imaging

Non-Invasive, Non-Contact Imaging of the Anterior Segment by Anterior Segment OCT

Robert Ritch, MD

Anterior segment imaging using ultrasound biomicroscopy (UBM) and slit lamp optic coherence tomography (SL-OCT) in patients using alpha-adrenergic blockers.

Robert Ritch, MD

In Vivo Three Dimensional Confocal Laser Scanning Microscopy of Anterior Segment Structures Using the HRT II Rostock Cornea Module

Robert Ritch, MD

Unilateral exfoliative glaucoma: comparing functional tests using short-wavelength automated perimetry, frequency doubling technology perimetry and multifocal visual evoked potential

Robert Ritch, MD

Evaluation of patients with normal-tension glaucoma (NTG) or high-tension glaucoma (HTG) using different visual field studies and nerve fiber layer imaging

Robert Ritch, MD

Functional and Structural Testing for Optic Nerve Disease

Robert Ritch, MD

Ocular Hypertension

A Multi-center, double-masked, randomized, placebo-controlled, ascending dose study of INS115644 ophthalmic solution in subjects with bilateral ocular hypertension or early open angle glaucoma.

Robert Ritch, MD

Randomized, Controlled, Multicenter Comparative Trial to Evaluate for the SOLX Gold Shunt for the Reduction of Intraocular Pressure (IOP) In Glaucomatous Eyes Following Failed Medical and Conventional Surgical Treatments

Robert Ritch, MD

Neuro Ophthalmology

NEW! Biomarker/Gene Expression Pilot Study on Ocular Myasthenia Gravis

Rudrani Banik, MD

Acute Demyelinating Optic Neuritis

NEW! Occlusion Therapy for Acute Optic Neuritis: A Pilot Study

Rudrani Banik, MD

Ocular Oncology

The Collaborative Ocular Melanoma Study

Paul Finger, MD

Ocular Trauma

Trauma Registry

 

Oculoplastic & Orbital Surgery

Thyroid Eye Disease Study

Robert Della Rocca, MD
Paul Latkany, MD

Refractive Surgery

SRP (Surgical Reversal of Presbyopia)

Barrie Soloway, MD

Retina

Age Related Macular Degeneration

NEW! AMD PHENOTYPE AND GENOTYPE STUDY (APGS)

Richard Rosen, MD

A Genetic Study of Macular Degeneration

Richard Rosen, MD

Dry Age Related Macular Degeneration

NEW! GEOGRAPHIC ATROPHY AMD STUDY

Richard Rosen, MD

End Stage Age Related Macular Degeneration

NEW! VISIONCARE’S IMPLANTABLE MINIATURE TELESCOPE (BY DR. ISAAC LIPSHITZ) ) IN PATIENTS WITH END-STAGE AGE-RELATED MACULAR DEGENERATION

Richard Rosen, MD

Wet Age Related Macular Degeneration

NEW! Serial Retinal Thickness Changes and Scotoma Size Measured with Lucentis Therapy measured Using the OCT Ophthalmoscope (OCT/SLO)® and the Foresee Preferential Hyperacuity Perimeter TM PROTOCOL FVF4193s

Richard Rosen, MD

Diabetic Eye Conditions

NEW! Genes in Diabetic Retinopathy Project

Robert Gentile, MD

Macular Pigment Density Supplementation in Type 2 Diabetes Trial

Richard Rosen, MD

Diabetic Macular Edema

NEW! CLINICAL EFFICACY OF INTRAVITREAL ADMINISTRATION OF BEVACIZUMAB COMBINED WITH NAVIGATED LASER (NAVILAS) TREATMENT IN PATIENTS WITH CLINICALLY SIGNIFICANT MACULAR EDEMA Protocol CAVNAV-2

Richard Rosen, MD

Macular Telangiectasia

A Natural History Study Of Macular Telangiectasia- The MacTel Study

Richard Rosen, MD

Retinal Degeneration Adaptive Optics Imaging

NEW! Assessing Photoreceptor Structure And Function In Normal And Diseased Retinae

Richard Rosen, MD

Retinal Imaging

Comparison of OCT-Opthalmoscope and Standard OCT Technology Instrument For the Imaging of Macular Hole Pathology

Richard Rosen, MD

Macular Pigment Density Measurements Using Auto Fluorescence HRA

Richard Rosen, MD

 

Uveitis

NEW! A Randomized, Double-masked, Placebo-controlled Study of the Safety and Efficacy of Gevokizumab in the Treatment of Active Non-infectious Intermediate, Posterior, or Pan-Uveitis.

C. Michael Samson, MD

NEW! The VISUAL Clinical Trials for Uveitis

Sanjay Kedhar, MD

Uveitis Genetics

C. Michael Samson, MD

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Want more information about Ophthalmology Research?

 

NYEE Eye Research Centers

Marrus Adaptive Optics Imaging Laboratory
State of the art, cutting edge, high-resolution adaptive optics (AO) Imaging System allows direct visualization of individual rod and cone photoreceptor cells, retinal pigment epithelium cells, and white blood cells. AO imaging has changed the way vision scientists and ophthalmologists see the retina, helping to clarify our understanding of retinal structure, function, and the etiology of various retinal pathologies.

Advanced Retinal Imaging Laboratory
This specialty facility explores new technologies for imaging the human retina in order to enhance our understanding of the anatomy, physiology and visual function.

Glaucoma Services
Clinical service at the forefront of innovation in diagnostic and therapeutic advances in the understanding and treatment of glaucoma.

Ocular Pathology Laboratory
A major referral center for the Metropolitan area and the Northeastern US.

The New York Glaucoma Institute
Created to support research into the basic causes of glaucoma, increase public awareness of glaucoma, and promulgate educational material for ophthalmologists, other physicians, and persons with glaucoma.

The Ocular Imaging Center
Ultrasound Biomicroscopy (UBM) and Optical Coherence Tomography (OCT) clinical databases.

The Shelley and Steven Einhorn Clinical Research Center
Today, scientists and physicians work in seven distinct areas, each devoted to enhancing the NYEE's focus on the advancement of ophthalmology though the development of technologies and involvement in clinical investigations aimed at conquering eye disease, preventing blindness, and restoring vision.

New York Medical College
Additional research facilities are located amongst affiliated hospitals and universities of the academic department.

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