The Ear Institute at New York Eye and Ear Infirmary of Mount Sinai (NYEE) leads and participates in many of the nation's most advanced basic science research projects and FDA clinical trials concerned with speech, language, hearing and balance disorders.
Areas of clinical research include:
- Speech perception "in noise" following bone anchored hearing aid implantation
- Hearing preservation following cochlear implantation in patients with residual hearing
- The diagnosis and treatment of balance disorders
- Surgical techniques and preservation of facial nerve function in skull base surgery
Basic science studies, performed in our laboratories at the New York Medical College, include:
- Research whose goal is to understand the mechanism of hair cell damage, which causes hearing loss and balance dysfunction, and to develop ways to prevent and reverse hair cell damage.
- Research designed to identify genes whose mutations cause hereditary hearing and balance deficits; and to develop diagnostic tools, preventive and therapeutic measures, and to increase the general understanding of inner ear biology.
- Research of the otoprotective role of gap junction blockade in aminoglycoside ototoxicity. Gap junctions are the sites of communication between adjacent cells, coupling cells electrically and chemically. Mutations in gap junction genes are associated with hearing loss and vestibular dysfunction, indicating their important role in the inner ear.