Advanced Retinal Imaging Center: Emerging Technologies
In addition to performing routine diagnostic tests on our patients and those of referring community ophthalmologists, the Advanced Retinal Imaging Laboratory and the Retina Center continues to actively participate in the development of new retinal imaging technologies.
In 1992 we made the transition to digital angiography imaging, which gave us instant access to fluorescein and indocyanine green imaging of our patients' retinas. In 1995 we acquired one of the fisrt prototype OCT systems in the world prior to its commercial introduction by Zeiss. From 1996 to 2000, we continued to add several innovative imaging devices including the Retinal Thickness Analyzer (Talia), RetCam 120(Massie Labs), 3D Ultrasound Tomography System (OTI), the Heterochromatic Flicker Photometer for macula pigment measurement (Maculometrics),and the Scanning Laser Ophthalmoscope (Rodenstock-Canon). Working with OTI on their 3D ultrasound tomographer , we help develop ultrasound volumetric topography and became their clinical laboratory for hardware and software advances. This system eventually evolved to the current OTI/OPKO/OPTOS system with multi-resolution ultrasound (10/20 MHz) and UBM (35/50 MHz) capabilities.
In 2001, through the generous support of the Leon Lane Foundation we sponsored research at the University of Kent, in the laboratory of Professor Adrian Podoleanu in coordination with Rishard Weitz of Optical Technologies Inc. (OTI) to develop a clinical prototype combined OCT/SLO designed for clinical retinal imaging. This machine became commercially available in 2005, and we continue to contribute to its development through clinical studies and apha-testing.
In 2002 with the opening of the Bendheim Retina Center, the most clinically advanced protype imaging systems were transferred from the laboratory to the center. A specially designed electrophysiology lab equipped with a Veris Mulifocal ERG system was added to the existing LKC ERG, under the direction of Alessandra Bertolucci, M.D. with the assistance of Robert Masini, Director of Imaging.
In 2006, we were the first to acquire a spectral-domain version of the OCT/SLO. We also sponsored development of the OCT/SLO/ICG, which integrated simultaneous digital ICG angiography with the OCT/SLO structural imaging. A time-domain anterior segment OCT/SLO prototype was also added which could acquire both saggital and coronal OCT scans of the anterior ocular segment.
With the advent of higher OCT/SLO speeds it became possible to to add functional imaging to the system and we helped to develop and introduce OCT/SLO Microperimetry with our OTI Research partner. This system is unique in it ability to correlate structure and function in a single series of studies.
In 2008 we acquired the Retinal Functional Imager (Optical Imaging), which gave us blood flow measurements and in 2012 the Optimap Retinal Oximeter was added to provide oxygen tension measurements of the fundus vessels. A modified Heidelberg Dual Wavelength Autofluorescent Imager for mapping macular pigment density was also acquired.
In 2009 we helped sponsor development of small-field ultrahigh resolution OCT/SLO which provided near adaptive optic quality detail in a clincal system. It provided clinical imaging of the photoreceptor matrix and the smallest capillaries in the macula.
Since 2011, we have transferred our clinical retinal microscopy efforts to the Marrus Adaptive Optics Lab, located within the Einhorn Clinical Research Center, which houses a variety of experimental structural and functional imaging systems.
Today the Retina Center is equipped with several state-of-the-art systems for OCT imaging, including the Heidelberg Spectralis, Zeiss Cirrus HD, Optos OCT/SLO Microperimeter and the Optovue Avanti RTVue XR. Physicians have a variety of options for angiography and autofluorecense imaging including Topcon Digital Fundus Photography, Heidelberg SLO Imaging, Optos Wide Angle SLO Imaging and Optovue OCT Angiography. We continue to add interested manufacturers as clinical research partners to ensure that our patients have access to the latest cutting-edge diagnostic imaging devices available.