Douglas K. Frank, M.D.
Assistant Professor of Otolaryngology

biosketch  

Current Research Projects:

• Intercellular Communication and Therapeutic Bystander Effects in Head and Neck Cancer

Selected Publications and Presentations:

Frank, DK. Gene Therapy for Head and Neck Cancer. Surgical Oncology Clinics of North America 2002; 11:589-606. [Abstract]

Nakashima T, Sun SY, Lotan R, Frank DK, Clayman G. All-Trans-Retinoic acid synergistically enhances the effect of adenovirus-mediated wild-type p53 gene transfer in head and neck squamous cell carcinoma. Presented at the 5th International Conference on Head and Neck Cancer, San Francisco, CA, July-August 2000.

Frank DK, Frederick MJ, Liu TJ, Clayman GL, A bystander effect in the adenovirus-mediated wild-type p53 gene therapy model of human squamous cell carcinoma of the head and neck. Clinical Cancer Research 1998; 4:2521-2527. [Abstract]

Frank DK, Frederick MJ, Liu TJ, Clayman GL. A bystander effect in the adenovirus-mediated wild-type p53 gene therapy model of human squamous cell carcinoma of the head and neck. Presented at the 40th Annual Meeting of the American Society for Head and Neck Surgery, Palm Beach, FL, May 1998.

Jan Geliebter, Ph.D.
Associate Professor
Department of Microbiology and Immunology
Department of Otolaryngology 

Frances Hannan, Ph.D.
Assistant Professor
Department of Cell Biology and Anatomy

Qiang Huang, Ph.D.
Assistant Professor of Otolaryngology

email

Current Research Projects:

• Comparative Genomic Hybridization

Selected Publications and Presentations:

Huang Q, Yu GP, McCormick SA, Mo J, Datta B, Mahimkar M, Lazarus P, Schaffer AA, Desper R, Schantz SP. Genetic diff erences detected by comparative genomic hybridization in head and neck squamous cell carcinomas from different tumor sites: Construction of oncogenetic trees for tumor progression. Genes Chromosomes and Cancer 2002; 34:224–233. [Abstract]

Huang Q, Schantz SP, Rao PH, Mo J, McCormick SA, Chaganti RSK. Improving degenerate oligonucleotide primed PCR-comparative genomic hybridization for analysis of DNA copy number changes in tumors. Genes Chromosomes and Cancer 2000; 28:395-403. [Abstract]

Ana H. Kim, M.D.
Assistant Professor of Otolaryngology

Current Research Projects:

• Role of gap junction in the inner ear.
• Inner ear hair cell regeneration after aminoglycoside induced ototoxicity. 
• Vestibulo-Collic Reflex in assessing vestibular function.
• Role of growth factors in tympanic membrane healing – patent pending.

View Publications and Presentations

Christopher Linstrom, M.D.
Professor of Otolaryngology

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Current Research Projects:

• Facial Nerve Function
• Power Reflectance
• Cochlear Implants
• Bone Anchored Hearing Aids
• Chronic Ear Disease

Selected Publications and Presentations:

Linstrom CJ, Silverman CA, Colson, D. Facial motion analysis with a video and computer system after treatment of acoustic neuroma. Otology & Neurotology 2002 4:572-579. [Abstract]

Linstrom CJ. Objective facial motion analysis in patients with facial nerve dysfunction. Laryngoscope. 2002 1129-1147. [Abstract]

Linstrom CJ, Silverman CA, Susman WM. Facial-motion analysis with a video and computer system: a preliminary report. American Journal of Otology 2000 1:123-129. [Abstract]

Linstrom CJ, Silverman CA, Rosen A, Meiteles LZ. (2001). Bone-conduction impairment in chronic ear disease. Annals of Otology, Rhinology and Laryngology 2002 110:437-441. [Abstract]

Linstrom CJ, Silverman CA, Rosen A, Meiteles LZ. Eustachian-tube endoscopy in patients with chronic ear disease. Laryngoscope 2000 110:1884-1889. [Abstract]

Michael Pitman , M.D.
Assistant Professor of Otolaryngology

Current Research Projects:

• Vocal Fold Paralysis
• Laryngeal Reinervation
• Spasmodic Dysphonia

View Publications and Presentations

Rick Roark, Ph.D.
Professor of Otolaryngology 
Director of Laryngology Research, New York Medical College

biosketch   email

Dr. Roark is trained in the areas of electrical, biomedical and computer engineering and mathematics. Dr. Roark's research interest include electromyography of laryngeal and facial muscles, digital signal processing of biometric signals, and quantification of voice and speech. He has pioneered precepts in Otolaryngology research that include the use of time-frequency and wavelet transforms for EMG analysis, pattern signature extraction, and the technology of Vector Laryngeal EMG. Dr. Roark's research has received funding from the NIH, NSF, corporate sponsors, and philanthropists. He serves as Associate Editor of IEEE Transactions on Biomedical Engineering and on the Editorial Board of Journal of Voice.

Current Research Projects:

• Vocal Fold Paresis and Paralysis
• Vector Laryngeal Electromyography
• Spasmodic Dysphonia
• Quadrifilar Electromyography in Facial Nerve Paralysis

Selected Publications and Presentations:

Roark RM, Li JCL, Schaefer SD, Adam A, De Luca CJ. Multiple Motor Unit Recordings of Laryngeal Muscles: The Technique of Vector Laryngeal EMG. Laryngoscope 2002, 112:2196-2201. [Abstract]

Li, JCL, Roark RM, Schaefer SD, Adam A. Decomposition of Laryngeal Electromyographic Signals. American Laryngological Association, Orlando, 2000.

Roark, RM., Dowling EM, DeGroat RD, Watson BC, Schaefer SD. Time-Frequency analysis of thyroarytenoid myoelectric activity in normal and spasmodic dysphonia subjects, Journal of Speech and Hearing Research 1995, 38:289-303. [Abstract]

De Luca CJ, Nawab S, Adam A, Roark R, Manto M. Precision decomposition II for EMG signals: An NIH bioengineering research project. XIVth Congress of the International Society of Electrophysiology and Kinesiology, Vienna, Austria, June 2002.

Roark RM, De Luca CJ, Schaefer SD, Li JCL, Adam A, Wong H. Multiple motor unit recordings of laryngeal myoelectric signals, 29th Annual Symposium: Care of the Professional Voice, The Voice Foundation, Philadelphia, June 2000.

Renato Rozental, M.D., Ph.D.
Associate Professor
Department of Cell Biology and Anatomy

Developmental neurobiology and diseases mediated by cell-cell communication via gap junction channels; impact of hypoxic-ischemic insults in the developing brain.

Howard Savage, Ph.D.
Professor of Otolaryngology 

biosketch |  email   

• Native Cellular Fluorescence of Thyroid Nodules

Selected Publications and Presentations:

Katz A, Savage HE, Schantz SP, McCormick SA, Alfano RR. Noninvasive native fluorescence imaging of head and neck tumors. Technology in Cancer Research and Treatment 2002; 1:9-7. [Abstract]

Gayen SK, Alrubaiee M, Savage H, Schantz SP, Alfano RR. Parotid gland tissues investigated by picosecond time-gat ed and optical spectroscopic imaging techniques. IEEE Journal on Selected Topics in Quantum Electronics 2001; 7:906-911. [Abstract]

Guo Y, Savage HE, Liu F, Schantz SP, Ho PP, Alfano RR. Subsurface structure of tissues investigated by noninvasive optical second harmonic tomography. Proceedings National Academy of Sciences USA 1999; 96:10854-10856. [Abstract]

Schantz SP, Kolli VK, Savage HE, Yu G, Shah JP, Harris DE, Katz A, Alfano RR. Huvos AG. In-vivo native cellular fluorescence and histologic characteristics of head and neck cancer. Clinical Cancer Research 1998; 4:1177-1182. [Abstract]

Stimson Schantz, M.D.
Professor of Otolaryngology 
Director of Resident Research

biosketch   email

Current Research Projects:

• The Increasing Problem of Head and Neck Cancer in the Young AdultEstrogen Metabolism and Thyroid Disease ProgressionNative Cellular Fluorescence of Thyroid Nodules Comparative Genomic Hybridization
• Use of Curcumin as a Chemopreventive Agent

Selected Publications and Presentations:

Schantz SP, Yu GP. Head and neck incidence trends in young Americans, 1973 – 1997, with a special analysis for tongue cancer. Otolaryngology and Head and Neck Surgery 2002; 128:268-274. [Abstract]

Huang Q, Schantz SP, Rao PH, Mo J, McCormick SA, Chaganti RSK. Improving degenerate oligonucleotide primed PCR-comparative genomic hybridization for analysis of DNA copy number changes in tumors. Genes Chromosomes and Cancer 2000; 28:395-403. [Abstract]

Yoo HJ, Sepkovic DW, Bradlow L, Yu GP, Sirilan HV, Schantz, SP. Estrogen metabolism as a risk factor for head and neck cancer. Otolaryngology Head and Neck Surgery 2001; 124:241-247. [Abstract]

Schantz SP, Vaidya SG. Green tea and leukoplakia. American Journal of Surgery 1997; 174:552-555. [Abstract]

Zhang ZF, Morganstern H, Spitz MR, Tashkin DP, Marshall JR, Hsu TC, Schantz SP. Environmental tobacco smoke and risk of head and neck squamous cell carcinoma. Cancer Epidemiology Biomarkers and Prevention 2000; 9:1043-1049. [Abstract]

Anthony Sclafani, M.D.
Professor of Otolaryngology 
Director, Division of Facial Plastic Surgery

biosketch  email

Dr. Sclafani has focused his research on expanding our understanding of synthetic facial implants and acellular human dermal grafts. These topics, together with research on healing periosteum, enhance our knowledge of wound healing. He has published over 50 articles in peer-reviewed medical journals, and has presented his work at regional, national and international medical meetings. Dr. Sclafani has been awarded both the Sir Harold Delf Gillies Award and the Ira Tresley Research Award by the American Academy of Facial Plastic & Reconstructive Surgery for excellence in research. He has received over $300,000 in research funding in the past 5 years. He is a senior associate editor of Facial Plastic Surgery and serves on the editorial board of Facial Plastic Surgery Clinics of North America.

Current Research Projects:

• Tissue Reaction and Persistence of Dermal Allografts Anthropometric Facial Analysis and Quantitative Measurements of Aesthetically Pleasant Face of a Korean-American Woman
• Modulation of Wound Response and Soft Tissue Ingrowth into Synthetic and Allogeneic Implants with Platelet Rich Plasma

Selected Publications and Presentations:

Sclafani AP, Fozo M, Romo T 3rd, McCormick SA. Strength and histology of periosteal fixation to bone after elevation. Arch Facial Plast Surg 2003; 5:63-66. [Abstract]

Sclafani AP, Fozo M, Romo T 3rd, McCormick SA. Strength and histology of periosteal fixation to bone after elevation. Arch Facial Plast Surg 2003; 5:63-66. [Abstract]

Sclafani AP, Romo T 3rd, Jacono AA. Rejuvenation of the aging lip with an injectable acellular dermal graft (Cymetra™). Arch Facial Plast Surg 2002; 4:252-257. [Abstract]

Sclafani AP, McCormick SA, Cocker R. Biophysical and microscopic analysis of homologous dermal and fascial materials for facial aesthetic and reconstructive uses. Arch Facial Plast Surg 2002; 4:164-171. [Abstract]

Sclafani AP. The multivectorial subperiosteal midface lift. Facial Plast Surg 2001; 17:29-36. [Abstract]

Sclafani AP, Romo T 3rd. Collagen, human collagen and fat: the search for a three-dimensional soft tissue filler. Facial Plast Surg 2001; 17:79-85. [Abstract]

Sclafani AP, Romo T 3rd, Jacono AA, McCormick SA, Cocker R, Parker A. Evaluation of acellular dermal graft (AlloDerm) for soft tissue augmentation: one year of clinical observations and histologic findings. Arch Facial Plast Surg 2001; 3:101-103. [Abstract]

Carol Silverman, Ph.D.
Adjunct Professor in Otolaryngology

biosketch |  email   

Current Research Projects:

• Cochlear implants and music perception
• Langeloth Foundation funded study in progress on the short-term and long-term efficacy of bone anchored hearing aids
• Facial-nerve dysfunction

Selected Publications and Presentations:

Linstrom CJ, Silverman CA, Colson, D. Facial motion analysis with a video and computer system after treatment of acoustic neuroma. Otology & Neurotology 2002 4:572-579. [Abstract]

Linstrom CJ, Silverman CS. Objective assessment of facial motion in persons with facial dysfunction. Paper presented at the IXth International Facial Nerve Symposium, School of Medicine, University of California, San Francisco, CA, July 2001.

Linstrom CJ, Silverman CA, Susman WM. Facial-motion analysis with a video and computer system: a preliminary report. American Journal of Otology 2000 1:123-129. [Abstract]

Linstrom CJ, Silverman CA, Rosen A, Meiteles LZ. (2001). Bone-conduction impairment in chronic ear disease. Annals of Otology, Rhinology and Laryngology 2002 110:437-441. [Abstract]

Linstrom CJ, Silverman CA, Rosen A, Meiteles LZ. Eustachian-tube endoscopy in patients with chronic ear disease. Laryngoscope 2000 110:1884-1889. [Abstract]

Raj K. Tiwari, Ph.D.
Associate Professor
Department of Microbiology and Immunology
Department of Otolaryngology 

See biosketch for research interests