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Research
Faculty
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Daniel Branovan, M.D. |
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General Otolaryngology |
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Robin Dyleski, M.D. |
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Pediatric Otolaryngology |
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Douglas K. Frank, M.D. |
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Head & Neck Surgical Oncology |
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Jan Geliebter,
Ph.D. |
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Thyroid Diseases |
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Frances Hannan, Ph.D. |
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Cell Biology and Anatomy |
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Qiang Huang, Ph.D. |
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Molecular Biology |
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Ana H. Kim, M.D. |
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Otology, Neurotology |
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James CL Li, M.D. |
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Electrophysiology |
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Christopher Linstrom, M.D. |
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Neurotology |
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Jane Madell, Ph.D. |
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Pediatric Audiology |
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Michael Pitman, M.D. |
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Laryngology |
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Rick M. Roark, Ph.D. |
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Bioengineering, Laryngology |
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Renato Rosenthal, M.D., Ph.D. |
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Cell Biology and Anatomy |
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Howard Savage, Ph.D. |
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Cellular Fluorescence |
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Steven Schaefer, M.D. |
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Laryngology, Rhinology |
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Stimson Schantz, M.D |
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Head & Neck Surgical Oncology |
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Anthony Sclafani, M.D. |
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Facial Plastics |
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Carol Silverman, Ph.D. |
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Hearing Science |
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Raj K.
Tiwari, Ph.D. |
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Thyroid Diseases |
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Guopei Yu, M.D. |
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Medical Statistics |
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Daniel I. Branovan, M.D.
Assistant
Professor of Otolaryngology |
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Robin Dyleski , M.D.
Associate Professor of Otolaryngology |
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Douglas K. Frank, M.D.
Assistant Professor of Otolaryngology
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Current Research Projects:
Selected Publications and Presentations:
Frank, DK. Gene Therapy for Head and Neck Cancer.
Surgical
Oncology Clinics of North America 2002; 11:589-606. [Abstract]
Nakashima T, Sun SY, Lotan R, Frank DK, Clayman G.
All-Trans-Retinoic acid synergistically enhances the effect of
adenovirus-mediated wild-type p53 gene transfer in head and neck
squamous cell carcinoma. Presented at the 5th International
Conference on Head and Neck Cancer, San Francisco, CA, July-August
2000.
Frank DK, Frederick MJ, Liu TJ, Clayman GL, A bystander effect in
the adenovirus-mediated wild-type p53 gene therapy model of human
squamous cell carcinoma of the head and neck. Clinical Cancer
Research 1998; 4:2521-2527. [Abstract]
Frank DK, Frederick MJ, Liu TJ, Clayman GL. A bystander effect in
the adenovirus-mediated wild-type p53 gene therapy model of human
squamous cell carcinoma of the head and neck. Presented at the 40th
Annual Meeting of the American Society for Head and Neck Surgery,
Palm Beach, FL, May 1998.
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Qiang Huang, Ph.D.
Assistant Professor of Otolaryngology
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Current Research Projects:
Selected Publications and Presentations:
Huang Q, Yu GP, McCormick SA, Mo J, Datta B, Mahimkar M, Lazarus
P, Schaffer AA, Desper R, Schantz SP. Genetic diff
erences detected
by comparative genomic hybridization in head and neck squamous cell
carcinomas from different tumor sites: Construction of oncogenetic
trees for tumor progression. Genes Chromosomes and Cancer
2002; 34:224–233. [Abstract]
Huang Q,
Schantz SP, Rao PH, Mo J, McCormick SA, Chaganti RSK. Improving
degenerate oligonucleotide primed PCR-comparative genomic
hybridization for analysis of DNA copy number changes in tumors. Genes Chromosomes and Cancer
2000; 28:395-403. [Abstract]
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Ana H. Kim, M.D.
Assistant Professor of Otolaryngology |
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Current Research Projects:
- Role of gap junction in the inner ear.
- Inner ear hair cell regeneration after aminoglycoside induced ototoxicity.
- Vestibulo-Collic Reflex in assessing vestibular function.
- Role of growth factors in tympanic membrane healing – patent pending.
View Publications and Presentations
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James CL Li, M.D.
Assistant Professor of Otolaryngology
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Dr. Li was trained in
otolaryngology at The New York Eye and Ear Infirmary. He also has
a background in engineering, with a Master’s degree in
electrical engineering. Dr. Li's research interest include
electromyography of laryngeal and facial muscles. His current
research project involves applying the technology of quadrifilar
electromyographic technique to facial paralysis. Dr. Li
currently has research funding from the Empire Clinical Research
Investigator Program.
Current Research Projects:
Selected Publications and Presentations:
Roark RM, Li JCL, Schaefer SD, Adam A, De Luca CJ. Multiple Motor
Unit Recordings of Laryngeal Muscles: The Technique of Vector
Laryngeal EMG. Laryngoscope 2002, 112:2196-2201. [Abstract]
Li, JCL, Roark
RM, Schaefer SD, Adam A.
Decomposition of Laryngeal Electromyographic Signals. American
Laryngological Association, Orlando, 2000.
Hoffman RA, Li JCL. Tetracaine Topical Anesthesia for Myringotomy.
Laryngoscope 2001; 111:1636-38. [Abstract]
Li JCL, Werner P, Cohen G. Lipid Peroxidation in Brain: Interaction
of L-DOPA/ Dopamine with Ascorbate and Iron. Neurodegeneration
1995 4:147-154. [Abstract]
Roark RM, De Luca CJ, Schaefer SD, Li JCL, Adam A, Wong H. Multiple
motor unit recordings of laryngeal myoelectric signals, 29th Annual
Symposium: Care of the Professional Voice,
The Voice Foundation, Philadelphia, June 2000.
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Christopher Linstrom, M.D.
Professor of Otolaryngology
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Current Research Projects:
Selected Publications and Presentations:
Linstrom CJ,
Silverman CA, Colson, D. Facial motion analysis with a video and
computer system after treatment of acoustic neuroma. Otology &
Neurotology 2002 4:572-579. [Abstract]
Linstrom CJ. Objective facial motion analysis in patients with
facial nerve dysfunction. Laryngoscope. 2002 1129-1147. [Abstract]
Linstrom CJ, Silverman CA, Susman WM. Facial-motion analysis with a
video and computer system: a preliminary report. American Journal
of Otology 2000 1:123-129. [Abstract]
Linstrom CJ, Silverman CA, Rosen A, Meiteles LZ. (2001).
Bone-conduction impairment in chronic ear disease. Annals of
Otology, Rhinology and Laryngology 2002 110:437-441. [Abstract]
Linstrom CJ, Silverman CA, Rosen A, Meiteles LZ. Eustachian-tube
endoscopy in patients with chronic ear disease. Laryngoscope
2000 110:1884-1889. [Abstract]
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Jane Madell , Ph.D.
Professor of Otolaryngology |
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Rick Roark, Ph.D.
Professor of Otolaryngology
Director
of Laryngology Research, New York Medical College
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Dr. Roark is trained in the areas
of electrical, biomedical and computer engineering and
mathematics. Dr. Roark's research interest include
electromyography of laryngeal and facial muscles, digital signal
processing of biometric signals, and quantification of voice and
speech. He has pioneered precepts in Otolaryngology research
that include the use of time-frequency and wavelet transforms
for EMG analysis, pattern signature extraction, and the
technology of Vector Laryngeal EMG. Dr. Roark's research has
received funding from the NIH, NSF, corporate sponsors, and
philanthropists. He serves as Associate Editor of IEEE
Transactions on Biomedical Engineering and on the Editorial
Board of Journal of Voice.
Current Research Projects:
Selected Publications and Presentations:
Roark RM, Li JCL, Schaefer SD, Adam A, De Luca CJ. Multiple Motor
Unit Recordings of Laryngeal Muscles: The Technique of Vector
Laryngeal EMG. Laryngoscope 2002, 112:2196-2201. [Abstract]
Li, JCL, Roark
RM, Schaefer SD, Adam A.
Decomposition of Laryngeal Electromyographic Signals. American
Laryngological Association, Orlando, 2000.
Roark, RM., Dowling
EM, DeGroat RD, Watson BC, Schaefer SD.
Time-Frequency analysis of thyroarytenoid myoelectric activity in
normal and spasmodic dysphonia subjects, Journal of Speech and
Hearing Research 1995, 38:289-303. [Abstract]
De Luca CJ, Nawab S, Adam A, Roark R, Manto M. Precision
decomposition II for EMG signals: An NIH bioengineering research
project.
XIVth Congress of the International Society of Electrophysiology and
Kinesiology, Vienna, Austria, June 2002.
Roark
RM, De Luca CJ, Schaefer SD, Li JCL, Adam A,
Wong H. Multiple motor unit recordings of laryngeal myoelectric
signals, 29th Annual Symposium: Care of the Professional Voice,
The Voice Foundation, Philadelphia, June 2000.
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Renato Rozental, M.D.,
Ph.D.
Associate Professor
Department of Cell Biology and Anatomy
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Research Interests:
Developmental neurobiology and diseases mediated by cell-cell communication via gap junction channels; impact of hypoxic-ischemic insults in the developing brain.
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Howard Savage, Ph.D.
Professor of Otolaryngology
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Current Research Projects:
Selected Publications and Presentations:
Katz A, Savage HE, Schantz SP, McCormick SA, Alfano
RR. Noninvasive native fluorescence imaging of head and neck tumors.
Technology in Cancer Research and Treatment 2002; 1:9-7. [Abstract]
Gayen SK, Alrubaiee M, Savage H, Schantz SP, Alfano RR. Parotid
gland tissues investigated by picosecond time-gat ed and optical
spectroscopic imaging techniques. IEEE Journal on Selected Topics
in Quantum Electronics 2001; 7:906-911. [Abstract]
Guo Y, Savage HE, Liu F, Schantz SP, Ho PP, Alfano RR. Subsurface
structure of tissues investigated by noninvasive optical second
harmonic tomography. Proceedings National Academy of Sciences USA
1999; 96:10854-10856. [Abstract]
Schantz SP, Kolli VK, Savage HE, Yu G, Shah JP, Harris DE, Katz A,
Alfano RR. Huvos AG. In-vivo native cellular fluorescence and
histologic characteristics of head and neck cancer. Clinical
Cancer Research 1998; 4:1177-1182. [Abstract]
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Steven Schaefer, M.D.
Professor of Otolaryngology
Chairman,
Department of Otolaryngology
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Dr. Schaefer's research interests
include the fields of rhinology, laryngology, voice, and head
and neck surgery...
Current Research Projects:
- Molecular biology and chemoprevention of thyroid carcinoma
- Bioengineering Partnership Grant, Program Project, Development Laryngeal Vector Electromyography
- Laryngeal reinnervation
Selected Publications and Presentations:
Schaefer SD, Soliemanzadeh P, Della Rocca DA, Yoo
GP, Maher EA, Milite JP, Della Rocca RC. Endoscopic and
transconjunctival orbital decompression for thyroid-related orbital
apex compression. Laryngoscope 2003; 113:508-513. [Abstract]
Roark RM, Li JCL, Schaefer SD, Adam A, De Luca CJ. Multiple Motor
Unit Recordings of Laryngeal Muscles: The Technique of Vector
Laryngeal EMG. Laryngoscope 2002; 112:2196-2201. [Abstract]
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Stimson Schantz, M.D.
Professor of Otolaryngology
Director
of Resident Research
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Current Research Projects:
Selected Publications and Presentations:
Schantz SP, Yu GP. Head and neck incidence trends in
young Americans, 1973 – 1997, with a special analysis for tongue
cancer. Otolaryngology and Head and Neck Surgery 2002;
128:268-274. [Abstract]
Huang Q, Schantz
SP, Rao PH, Mo J, McCormick SA, Chaganti RSK. Improving degenerate
oligonucleotide primed PCR-comparative genomic hybridization for
analysis of DNA copy number changes in tumors. Genes
Chromosomes and Cancer 2000; 28:395-403. [Abstract]
Yoo HJ, Sepkovic DW, Bradlow L, Yu GP, Sirilan HV, Schantz, SP.
Estrogen metabolism as a risk factor for head and neck cancer.
Otolaryngology Head and Neck Surgery 2001; 124:241-247. [Abstract]
Schantz SP, Vaidya SG. Green tea and leukoplakia. American
Journal of Surgery 1997; 174:552-555. [Abstract]
Zhang ZF, Morganstern H, Spitz MR, Tashkin DP, Marshall JR, Hsu TC,
Schantz SP. Environmental tobacco smoke and risk of head and neck
squamous cell carcinoma. Cancer Epidemiology Biomarkers and
Prevention 2000; 9:1043-1049. [Abstract]
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Anthony Sclafani, M.D.
Professor
of Otolaryngology
Director,
Division of Facial Plastic Surgery
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Dr. Sclafani has focused his
research on expanding our understanding of synthetic facial implants and
acellular human dermal grafts. These topics, together with research on healing
periosteum, enhance our knowledge of wound healing. He has published over 50
articles in peer-reviewed medical journals, and has presented his work at
regional, national and international medical meetings. Dr. Sclafani has been
awarded both the Sir Harold Delf Gillies Award and the Ira Tresley Research
Award by the American Academy of Facial Plastic & Reconstructive Surgery for
excellence in research. He has received over $300,000 in research funding in the
past 5 years. He is a senior associate editor of Facial Plastic Surgery and
serves on the editorial board of Facial Plastic Surgery Clinics of North
America.
Current Research Projects:
Selected Publications and Presentations:
Sclafani AP,
Fozo M, Romo T 3rd, McCormick SA. Strength and histology of periosteal
fixation to bone after elevation. Arch Facial Plast Surg 2003; 5:63-66. [Abstract]
Sclafani AP, Fozo M, Romo T 3rd, McCormick SA. Strength and histology of
periosteal fixation to bone after elevation. Arch Facial Plast Surg 2003;
5:63-66. [Abstract]
Sclafani AP, Romo T 3rd, Jacono AA. Rejuvenation of the aging lip with an
injectable acellular dermal graft (Cymetra™). Arch Facial Plast Surg
2002; 4:252-257. [Abstract]
Sclafani AP, McCormick SA, Cocker R. Biophysical and microscopic analysis of
homologous dermal and fascial materials for facial aesthetic and reconstructive
uses. Arch Facial Plast Surg 2002; 4:164-171. [Abstract]
Sclafani AP. The multivectorial subperiosteal midface lift. Facial Plast Surg
2001; 17:29-36. [Abstract]
Sclafani AP, Romo T 3rd. Collagen, human collagen and fat: the search for a
three-dimensional soft tissue filler. Facial Plast Surg 2001; 17:79-85. [Abstract]
Sclafani AP, Romo T 3rd, Jacono AA, McCormick SA, Cocker R, Parker A. Evaluation
of acellular dermal graft (AlloDerm) for soft tissue augmentation: one year of
clinical observations and histologic findings. Arch Facial Plast Surg 2001;
3:101-103. [Abstract]
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Carol Silverman, Ph.D.
Adjunct Professor in Otolaryngology
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Current Research Projects:
- Cochlear implants and music perception
- Langeloth Foundation funded study in progress on the short-term and long-term efficacy of bone anchored hearing aids
- Facial-nerve dysfunction
Selected Publications and Presentations:
Linstrom CJ, Silverman CA, Colson, D. Facial motion analysis with a
video and computer system after treatment of acoustic neuroma.
Otology & Neurotology 2002 4:572-579. [Abstract]
Linstrom CJ, Silverman CS. Objective assessment of facial motion in
persons with facial dysfunction. Paper presented at the
IXth International Facial Nerve Symposium, School of
Medicine, University of California, San Francisco, CA, July 2001.
Linstrom CJ, Silverman CA, Susman WM. Facial-motion analysis with a
video and computer system: a preliminary report. American Journal
of Otology 2000 1:123-129. [Abstract]
Linstrom CJ, Silverman CA, Rosen A, Meiteles LZ. (2001).
Bone-conduction impairment in chronic ear disease. Annals of
Otology, Rhinology and Laryngology 2002 110:437-441. [Abstract]
Linstrom CJ, Silverman CA, Rosen A, Meiteles LZ. Eustachian-tube
endoscopy in patients with chronic ear disease. Laryngoscope
2000 110:1884-1889. [Abstract]
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Guopei Yu, M.D., M.P.H.
Assistant Professor
of Otolaryngology
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Dr. Yu was trained in medicine,
public health, and biostatistics. He also received a one-year
post-doctoral fellowship in epidemiology at Harvard School of
Public Health. Dr. Yu had cooperative cancer research projects
with Harvard University. As Co-Principal Investigator, he also
cooperates with UCLA for an NCI-granted project on stomach
cancer. Dr. Yu is Head of the Biostatistics and Epidemiology
Service at The New York Eye and Ear Infirmary and Assistant
Professor of Otolaryngology at New York Medical College. His
current research interests are in the areas of clinical
epidemiology, health services research, and in applications of a
variety of national databases on health care and disease
registry that support these and other research projects.
Current Research Projects:
Selected Publications and Presentations:
Yu GP, Hsieh CC, Yu
SZ, Wang LY, Jin TH. Green-tea
consumption and reduced risk of stomach cancer, a population-based
case-control study in Shanghai. Cancer Causes & Control 1995;
6-532-538. [Abstract]
Yu GP, Ostroff JS, Zhang ZF, and Schantz SP. Smoking history and
cancer patient survival: a hospital cancer registry study. Cancer
Detection and Prevention 1997; 21:497-509. [Abstract]
Setiawan VW, Zhang ZF, Yu GP, et al. GSTT1 and GSTM1 null genotypes
and the risk of gastric cancer: a case-control study in Chinese
population. Cancer Epidemiology Biomarker and Prevention
2000; 9(1):73-80. [Abstract]
Lu ML, Orntoft TF, Wikman F, Charytonowicz E, Rabbani F, Zhang ZF,
Yu GP, Cordon-Cardo C. Impact of alterations affecting the p53
pathway in bladder cancer: impact on clinical outcome. Clinical
Cancer Research 2002; 8:171-179. [Abstract]
Schantz SP, Yu GP. Head and neck incidence trends in young
Americans, 1973 – 1997, with a special analysis for tongue cancer.
Otolaryngology and Head and Neck Surgery 2002; 128:268-274. [Abstract]
Yu GP, Zhang ZF, Hsu TC, Spitz MR, Schantz SP. Family history of
cancer mutagen sensitivity, and increased risk of head and neck
cancer: Cancer Letters 1999; 146:93-101. [Abstract]
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Publications
& Conference Presentations
Members
of the Department actively share the results of their research with the
professional community, both through presentations at national and
international conferences and via peer-reviewed print media. Select a research program
for further details about publications, presentations,
and staff.
Funding
& Grants
Otolaryngology
research is funded by both private and public agencies, including the
National Institutes of Health. Click
here for more information.
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