Principal
Investigator: James CL Li, M.D.
Enrollment
Status: Open
Objective:
Facial nerve weakness is a devastating condition
that can be that result of multitude of causes, including infection, trauma
and surgery. The degree of injury can range from mild weakness to complete
paralysis. Our understand and treatment for facial nerve injury is still
limited. One objective is to understand facial nerve injury from an
electrophysiological standpoint. This will lead to better assessment of degree
of injury soon after its onset and the likelihood for good recovery. Studies
involving laryngeal nerves are likewise underway in the Department.
Overview:
This project is studying facial nerve disorder
using advanced electromyographic techniques. Special recording probes (Quadrifilar)
and a signal processing algorithm allows multi-vector recording and analysis
of electrical signals from a muscle. Our Department is applying this new
technology to a patient population having unilateral facial nerve weakness for
the purpose of improving assessment (diagnosis) and prediction of recovery
(prognosis), which has historically proven difficult for this clinical
condition. This project is funded by an Empire Clinical Research Investigator
Award.
Departmental
Co-Investigators are Rick Roark,
Ph.D. and Steven Schaefer,
M.D.
Eligibility:
Research subjects are
being recruited for this study. If you are a physician treating
unilateral vocal fold paresis of known etiology, please contact Dr. Li
for participation details.
Contact
Information: James CL Li,
M.D., (212) 979-4200
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