Tumor Types and Their Origins


Nasal and anterior skull base tumors may arise from any of the tissue constituting the nose [1], sinuses (ethmoid sinuses [2], maxillary sinuses [3] ) and adjacent structures (skull base 4).

A brief list of tissues and their respective tumors is included below:

Tissue Benign Tumors Malignant Tumors

Mucous Membrane

Inverting Papilloma

Squamous Cell Carcinoma
Melenoma

Mucous Membrane Glands

Pleomorphic Adenoma

Adenocarcinoma
Mucoepidermoid Carcinoma
Adenoid Cystic Carcinoma

Olfactory and Neural Tissues

Neurilemmomas
Neurofibromas

Esthesioneurblastomas

Extranodal Lymphatic Tissues

 

Lymphoma

Cartilage

Chondroma

Chondrosarcoma

Bone

Osteoma

Osteogenic Sarcoma

Muscle

Leiomyoma

Leiomyosarcoma

Blood Vessels

Hemangiomas
Angiofibromas

Hemangiopericytomas

Notochord

 

Chordoma

 

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Signs and Symptoms of Tumors

Signs and symptoms of nasal and anterior skull base tumors reflect the location and type of tumor. Many of these tumors present with nasal airway obstruction and nose bleed (epistaxis). A few tumors occur in one gender and age group, rather than in the general population. Angiofibroma, a vascular tumor arising in posterior nose, is an example of a benign tumor seen in adolescent males who most often complain of nose bleeds and nasal airway obstruction. 

In contrast, malignant neoplasms of sinuses arise in both genders, and may have a variable presentation. In addition to potential nasal complaints, sinus tumors can invade the adjacent eye and brain. Symptoms might include impaired or double vision, or in very advanced disease, altered consciousness.

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