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Academic Faculty Services: Management of Nasal and Anterior Skull Base Tumors
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Tumor Types and Their Origins

Nasal and anterior skull base tumors may arise from any of the tissue constituting the nose [1], sinuses (ethmoid sinuses [2], maxillary sinuses [3] ) and adjacent structures (skull base 4).

A brief list of tissues and their respective tumors is included below:

 
Tissue Benign Tumors Malignant Tumors
Mucous Membrane Inverting Papilloma Squamous Cell Carcinoma
Melenoma
Mucous Membrane Glands Pleomorphic Adenoma Adenocarcinoma
Mucoepidermoid Carcinoma
Adenoid Cystic Carcinoma
Olfactory and Neural Tissues Neurilemmomas
Neurofibromas
Esthesioneurblastomas
Extranodal Lymphatic Tissues   Lymphoma
Cartilage Chondroma Chondrosarcoma
Bone Osteoma Osteogenic Sarcoma
Muscle Leiomyoma Leiomyosarcoma
Blood Vessels Hemangiomas
Angiofibromas
Hemangiopericytomas
Notochord   Chordoma
 

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Signs and Symptoms of Tumors

Signs and symptoms of nasal and anterior skull base tumors reflect the location and type of tumor. Many of these tumors present with nasal airway obstruction and nose bleed (epistaxis). A few tumors occur in one gender and age group, rather than in the general population. Angiofibroma, a vascular tumor arising in posterior nose, is an example of a benign tumor seen in adolescent males who most often complain of nose bleeds and nasal airway obstruction. 

In contrast, malignant neoplasms of sinuses arise in both genders, and may have a variable presentation. In addition to potential nasal complaints, sinus tumors can invade the adjacent eye and brain. Symptoms might include impaired or double vision, or in very advanced disease, altered consciousness.

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