New York Eye and Ear Infirmary
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Stimson Schantz, MD, FACSStimson Schantz, M.D., F.A.C.S.

Chief, Head & Neck Surgery
Professor of Otolaryngology
Head & Neck Surgery, General Otolaryngology, Thyroid Center
310 E. 14th Street
New York, NY 10003
TEL: (212) 979-4535
FAX: (212) 979-4315 
Email: sschantz@nyee.edu   |   Physician Profile

Publications

Peer-reviewed Papers

  1. Schantz SP, O'Neill J, Skolnick M. Improved survival associated with postoperative wound infection in laryngeal cancer. An analysis of its therapeutic implications. Otolaryngology Head and Neck Surgery 1980; 412:417.

  2. Schantz SP, Potter JF. Primary parotid cancer Factors influencing recurrence. American Surgeon 1983; 49:9 13.

  3. Schantz SP, Coffey RJ. The role of prophylactic gastroenterostomy in pancreatic cancer. American Journal of Surgery 1984; 147:793 796.

  4. Schantz SP, Romsdahl MM, Babcock GF, Nishioka K, Goepfert H. The effect of surgery on natural killer cell activity in head and neck cancer patients: In vitro reversal of a post peratively suppressed immunosurveillance system. Laryngoscope 1985; 95:588 594.

  5. Schantz SP, Poisson L. Natural killer cell response to regional lymph node metastases. Archives Otolaryngology Head and Neck Surgery 1986; 112:545 551.

  6. Schantz SP, Lira E, Taylor D. Diminished Leu 11+ NK populations in head and neck cancer patients. Surgical Forum 1986; 37:573 576.

  7. Schantz SP, Shillitoe EJ, Brown B, Campbell B. Natural killer cell activity and head and neck cancer: A clinical assessment. Journal of the National Cancer Institute 1986; 77:869 875.

  8. Schantz SP, Guillamondegui OM. Pharyngeal carcinoma and natural killer cell activity. American Journal of Surgery 1986; 152:467 474.

  9. Schantz SP, Goepfert HG. Multimodality therapy and distant metastases: The impact of natural killer cell activity. Archives Otolaryngology Head and Neck Surgery 1987; 113:1207 1213.

  10. Dimery I, Nishioka K, Grossie UB, Schantz S, Robbins KT, Byers R, Hong WK, Ota D. Polyamine metabolism in squamous cell carcinoma of the oral cavity, adjacent and normal oral mucosa. American Journal of Surgery 1987; 154:429 433.

  11. Schantz SP, Brown BW, Lira E, Taylor DL, Beddingfield N. Evidence for the role of natural immunity in the control of metastatic spread of head and neck cancer. Cancer Immunology Immunotherapy 1987; 25:141 145.

  12. Schantz SP, Peters L. Patterns of recurrence from head and neck cancer: An immunologic perspective. American Journal of Clinical Oncology 1987; 10:469 474.

  13. Schantz SP, Weber RS, Carey TE. Growth and progression of head and neck cancer: A report of the Upper Aerodigestive Cancer Task Force Workshop. Head and Neck Surgery 1988; 10:177 186.

  14. Schantz SP, Byers RM, Goepfert H. Tobacco and cancer of the tongue in young adults. Journal of the American Medical Association 1988; 259:1943 1944.

  15. Schantz SP, Liu FJ, Taylor D, Beddingfield N, Weber RS. Circulating IgA and its relationship to cellular immunity in the head and neck cancer patient. Laryngoscope 1988; 98:671 678.

  16. Schantz SP, Savage HE, Brown BW, Reuben JM, Hong WK, Rossen RD. The association of levels of circulating C1q binding macromolecules with induction chemotherapy response in head and neck cancer patients. Cancer Research 1988; 48:5868 5873.

  17. Schantz SP, Byers RM, Goepfert H, Shallenberger RS, Beddingfield N. The implication of tobacco use in the young adult with head and neck cancer. Cancer 1988; 62:1374 1380.

  18. Robbins KT, Byers RM, Cole R, Fainstein V, Guillamondegui OM, Schantz SP, Weber RS, Wolf P, Goepfert H. Successful wound prophylaxis with metronidazole in head and neck surgical oncology. Laryngoscope 1988; 98:803 807.

  19. Wolf GT, Al Sarraf M, Crissman JD, et al. Head and neck oncology research a summary of the second international head and neck oncology research conference. Head and Neck Surgery 1988; Supplement II:590 596.

  20. Schantz SP, Hsu TC. Head and neck cancer patients express increased clastogen induced chromosome fragility. Head Neck 1989; 11:337 343.

  21. Weber RS, Byers RM, Lichtiger B, Guillamondegui OM, Ballantyne AJ, Campbell B, Schantz SP, Hankins P, Pou A, Goepfert H. Blood conservation: A technique for reducing blood loss in head and neck surgery. Head and Neck 1989; 11:318 325.

  22. Schantz SP, Savage HE, Racz T, Liu FJ, Brown BW, Rossen RD, Hong WK. Immunologic determinants of head and neck cancer response to induction chemotherapy. Journal of Clinical Oncology 1989; 17:857 864.

  23. Spitz MR, Hsu TC, Fueger JJ, Ainslie N, Schantz SP. Chromosomal sensitivity to bleomycin induced mutagenesis in patients with upper aerodigestive cancers: A case control analysis. Cancer Research 1989; 49:4626 4628.

  24. Hsu TC, Johnston DA, Cherry LM, Ramkissoon D, Schantz SP, Jessup JM, Winn RD, Shirley L, Furlong C. Sensitivity to genotoxic effects of bleomycin in humans: Possible relationship to environmental carcinogenesis. International Journal of Cancer 1989; 43:403 409.

  25. Schantz SP, Liu FJ. An immunologic profile of young adults with head and neck cancer. Cancer 1989; 64:1232 1237.

  26. Schantz SP, Savage HE, Racz T, Taylor DL, Sacks PG. Natural killer cells and metastases from pharyngeal carcinoma. American Journal of Surgery 1989; 158:361 366.

  27. Racz T, Sacks PG, Taylor DL, Schantz SP. Natural killer cell lysis of head and neck cancer. Archives Otolaryngology Head and Neck Surgery 1989; 115:1322 1328.

  28. Schantz SP, Hsu TC Ainslie N, Moser RP. Young adults with head and neck cancer express increased susceptibility to mutagen induced chromosomal damage. Journal of American Medical Association 1989; 262:3313 3315.

  29. Schantz SP, Ordonez NG, Terry NHA, Racz T, Taylor DL, Bugis S, Sacks PG. Differential sensitivity of head and neck cancers to non major histocompatibility restricted killer cell activity. Journal of Surgical Research 1990; 48:154 164.

  30. Hsu TC, Shillitoe EJ, Cherry LM, Lin Q, Schantz SP, Furlong C. Cytogenetic characterization of 20 lymphoblastoid lines derived from human individuals differing in bleomycin sensitivity. In Vitro Cellular and Developmental Biology 1990; 26:80 84.

  31. Racz T, Sacks PG, Van NT, Taylor DL, Young G, Bugis S, Savage HE, Schantz SP. The analysis of natural killer cell activity by flow cytometry. Archives Otolaryngology Head and Neck Surgery 1990; 116:440 446.

  32. chantz SP, Savage HE, Brown BW, Young G, Liu FJ, Reger G, Newman RA. The significance of C1q binding macromolecules within the head and neck cancer patient. Cancer Research 1990; 50:4349 4354.

  33. Bugis SP, Lotzova E, Savage HE, Hester JP, Racz T, Sacks PG, Schantz SP. Inhibition of LAK generation by blocking factors in sera of patients with head and neck cancer. Cancer Immunology Immunotherapy 1990; 31:176 181.

  34. Putnam JB, Schantz SP, Pugh WC, Hickey RC, Samaan NA, Garza R, Suda RW. Extended en bloc resection of primary mediastinal parathyroid carcinoma. Annals of Thoracic Surgery 1990; 50:138 140.

  35. Clayman GL, Savage HE, Ainslie N, Liu FJ, Schantz SP. Serologic determinants of survival in patients with squamous cell carcinoma of the head and neck. American Journal of Surgery 1990; 60:434 442.

  36. Hong WK, Lippman SM, Itri L, Karp D, Lee JS, Byers RM, Schantz S, Kramer A, Lotan R, Dimery I, Peters L, Brown B, Goepfert H. Prevention of second malignancy in head and neck cancer with 13 cis retinoic acid. New England Journal of Medicine 1990; 323:795 801.

  37. Schantz SP, Clayman G, Liu FJ, Lavedan P, Taylor DL, Pellegrino C, Savage H. The in vivo biologic effect of interleukin 2 and interferon alpha on natural immunity in head and neck cancer patients. Archives of Otolaryngology Head and Neck Surgery 1990; 116:1302 1308.

  38. Schantz SP, Spitz ML, Hsu TC. Mutagen sensitivity in patients with head and neck cancers: A biologic marker for risk of multiple primary malignancies. Journal of the National Cancer Institute 1990; 82:1773 1775.

  39. Sacks PG, Taylor DL, Racz T, Schantz SP. A multicellular spheroid model to study non major histocompatibility restricted immune function against head and neck cancer. Cancer Immunology Immunotherapy 1990; 32:195 201.

  40. Riley LB, Pellis NR, Schantz, SP, Freedman RS, Balch CM, Itoh K. Humoarl modulation of lymphokine activated killer (LAK) cell induction in humans. IgG related and non IgG related inhibitors in sera from cancer patients. International Journal of Cancer 1990; 46:785-791.

  41. Seider MJ, Cleary KR, Van Tassel P, Alexanium R, Schantz SP, Fuller L, Frias A. Plasma cell granuloma in the nasal cavity treated by radiation therapy. Cancer 1991; 67:929-932.

  42. Lavedan P, Savage HE, Lee YY, Young G, Schantz SP. Circulating C1q binding macromolecules and its relationship to radiographic characteristics of laryngeal cancer. Archives of Otolaryngology Head and Neck Surgery 1991; 117:292-296.

  43. Clayman GL, Liu FJ, Taylor DL, Savage HE, Lavedan P, Buchsbaum RM, Trujillo JM, Schantz SP. Immunomodulation of the induction phase of lymphokine-activated killer activity by acute phase proteins. Otolaryngology Head Neck Surgery 1991; 105:234-235.

  44. Schantz SP, Ordonez NG. Quantitation of natural killer cell function and risk of metastatic poorly differentiated head and neck cancer. Natural Immunity and Cell Growth Regulation 1991; 10:278-288.

  45. Trizna A, Schantz SP, Hsu TC. Effects of N-acetyl-L-cysteine and ascorbic acid on mutagen-induced chromosomal sensitivity in head and neck cancer patients. American Journal of Surgery 1991; 162:294-298.

  46. Clayman GL, Grimm E, Taylor DL, Schantz SP. Immunologic profile of a patient with dyskeratosis congenita. Immunology & Allergy Practice 1992; 14(4):17-24. 

  47. Clayman GL, Lui FJ, Savage HE, Taylor DL, Lavedan P, Buchsbaum RM, Pellegrino C, Trujillo JM, Young G, Goepfert H, Schantz SP. Acute phase proteins in head and neck cancer patients treated with interleukin-2. Archives of Otolaryngology Head and Neck Surgery 1992; 118:41-48.

  48. Lippman SM, Parkinson DR, Itri L, Weber RS, Schantz SP, Ota DM, Schusterman MA, Gutterman JU, Krakoff IH, Hong WK. Isotretinoin plus interferon-alpha: Effective therapy for advanced squamous cell carcinoma of the skin. Journal of the National Cancer Institute 1992; 84:235-241.

  49. Trizna Z, Hsu TC, Schantz SP. Protective effects of vitamin E against bleomycin-induced genotoxicity in head and neck cancer patients in-vitro. Anticancer Research 1992; 12:325-328.

  50. Schantz SP, Dimery I, Lippman S, Clayman GL, Pellegrino C, Morice R. A phase II study of interleukin-2 and interferon-alpha against head and neck cancer. Investigational New Drugs 1992; 10:217-223.

  51. Clayman GL, Young G, Taylor DL, Lavedan P, He X, Savage HE, Schantz SP. Detection of regulatory factors of lymphokine-activated killer cell activity in head and neck cancer patients treated with interleukin-2 and interferon-alpha. Annals of Otology, Rhinology and Laryngology 1992; 101:909-915.

  52. Spitz MR, Sider SG, Schantz SP, Newell GR. The association of malignancies of the upper aerodigestive tract and uterine cervix. Head and Neck 1992; 14:347-351.

  53. Trizna Z, Hsu TC, Schantz SP, Hong WK. Anticlastogenic effects of 13-cis-retinoic acid in vitro. European Journal of Cancer 1992; 29A:137-140.

  54. Lydiatt DD, Savage HE, Clayman GL, Liu FJ, Sample D, Schantz SP. Serologic determinants in patients with head and neck cancer: Validating a clinical prediction model. Laryngoscope 1993; 103:13-16.

  55. Bondy ML, Spitz MR, Halabi S, Fueger JJ, Schantz SP, Sample D, Hsu TC. Association between family history of cancer and mutagen sensitivity in upper aerodigestive tract cancer patients. Epidemiology Biomarkers and Prevention 1993; 2:103-107.

  56. Das C, Schantz SP, Shillitoe EJ. Antibody to a mutagenic peptide of herpes simplex virus in young adult patients with cancer of the head and neck. Oral Surgery 1993; 75:610-614.

  57. Shillitoe EJ, Hecht S, Spitz M, Schantz SP. Environmental carcinogenesis and its prevention: The head and neck cancer model (a meeting report). Cancer Res 1993; 53:2189-2191.

  58. Schantz SP, Savage HE, Tang GC, Sacks PG, Silverberg M, Alfano RR. Tissue autofluorescence spectroscopy as an intermediate endpoint for chemopreventive agents. Proceedings of International Society for Optical Engineering 1993; 1887;25:195-205.

  59. Spitz MR, Fueger JJ, Schantz SP, Sample D, Hsu TC. Mutagen sensitivity in upper aerodigestive tract cancer: A case-control analysis. Cancer Epidemiology Biomarkers and Prevention 1993; 2: 103-106.

  60. Clayman GL, Taylor DL, Liu FJ, Lavedan P, Savage HE, Buchsbaum RM, Trujillo JM, Schantz SP. Serum and acute phase protein modulation of effector phase of LAK cells. Laryngoscope 1993; 103:299-307.

  61. Woods KV, Shillitoe EJ, Spitz MR, Schantz SP, Adler-Storthz K. Analysis of human papillomavirus DNA in oral squamous cell carcinomas. Oral Pathol and Medicine 1993; 22:101-108.

  62. Trizna Z, Schantz SP, Lee JJ, Spitz MR, Goepfert H, Hong WK. In-vitro protective effects of chemopreventive agents on mutagen-induced genotoxicity in head and neck cancer patients. Cancer Detection and Prevention 1993; 17:575-583.

  63. Vlock DR, Schantz SP, Savage HE, Fisher SG, Carey TE, Wolf GT. Clinical correlates of circulating immune complexes and antibody reactivity in squamous cell carcinoma of the head and neck. Journal of Clinical Oncology 1993; 11:2427-2433.

  64. Hsu TC, Savaroj N, Trizina Z, Feun L, Furlong CL, Schantz SP, Shirly LR. Cytogenetic studies on the in-vitro genotoxicity of 4-nitroquinolone-1-oxide on human lymphocytes. International Journal of Oncology 1993; 3:823-826.

  65. Hsu TC, Feun L, Trizna Z, Savaraj N, Shirley LR, Furlong CL, Schantz SP, Weber RS, Shen TJ, Kucek O. Differential sensitivity among three human subpopulations in response to 4-nitroquinolone-1-oxide and to bleomycin. International Journal of Oncology 1993; 3:827-830.

  66. Davidson B, Hsu TC, Chaganti R, Schantz SP. The genetics of tobacco-induced cancer. Archives of Otolaryngology Head and Neck Surgery 1993; 119:1198-1205.

  67. Silberberg MB, Savage HE, Tang GC, Sacks PG, Alfano RR, Schantz SP. Detecting retinoic acid induced biochemical alterations in squamous cell carcinoma using intrinsic fluorescence spectroscopy. Laryngoscope 1994; 104:278-283.

  68. Kraus, DH, Pfister DG, Harrison LB, Shah JP, Spiro RH, Armstrong JG, Fass DE, Zelefsky M, Schantz SP, Weiss HM, Wang RC, Bosl GJ, Strong EW. Larynx preservation with combined chemotherapy and radiation therapy in advanced hypopharynx cancer. Otolaryngology Head and Neck Surgery 1994; 111:31-38.

  69. Sreekantaiah C, Rao PH, Xu L, Sacks PG, Schantz SP, Chaganti RSK. Specific deletions in 3p, 4q, 5q, 8p, 10q and 18q characterize cell lines derived from squamous cell carcinomas of the head and neck. Genes Chromosomes and Cancer 1994; 11:29-39.

  70. Glasgold R, Glasgold M, Savage H, Pinto J, Alfano R, Schantz S. Tissue autofluorescence as an intermediate endpoint in NMBA-induced esophageal carcinogenesis. Cancer Letters 1994; 82:33-41.

  71. Sacks PG, Racz T, Schantz SP, Rosenblum MG. Growth inhibition by  and  interferon of MDA 886Ln monolayer cells and multicellular tumor spheroids (MTS): a differentiation therapy model for squamous cell carcinoma. Archives of Otolaryngology: Head and Neck Surgery 1994; 120:1267-1272.

  72. Franchesci D, Savage H, Alfano R, Schantz S. In-vivo fast fourier transform analysis of the autofluorescence of normal and neoplastic upper aerodigestive mucosa. Surgical Forum 1994; 45:488-493.

  73. Spitz MR, Hoque A, Trizna Z, Schantz SP, Amor CL, Bondy ML, Hong W, Hsu TC. Mutagen sensitivity as a risk factor for second malignant tumors following upper aerodigestive tract malignancies. Journal National Cancer Institute 1994; 86:1681-1684.

  74. Sturgis E, Sacks PG, Masui H, Mendelsohn J, Schantz SP. The effects of anti-epidermal growth factor receptor antibody 528 on the proliferation and differentiation of head and neck cancer. Otolaryngology Head and Neck Surgery 1994; 111:633-633.

  75. Xu L, Davidson BJ, Vindavally VV, Murty S, Sacks PG, Garin-Chesa P, Zlotolow IM, Schantz SP, Chaganti RSK. p53 mutations and cyclin D1 amplification in squamous cell carcinoma of head and neck. International Journal of Cancer 1994; 59:383-387.

  76. Yellin SA, Davidson BJ, Pinto JT, Sacks PG, Qiao C, Schantz SP. Relationship of gluathione and glutathione-S-tranferase to cisplatinum sensitivity in human head and neck squamous carcinoma cell lines. Cancer Letters 1994; 85:223-232.

  77. Lydiatt WM, Davidson BJ, Shah JP, Schantz SP, Chaganti, R. The relationship of loss of heterozygosity to tobacco and alcohol exposure and early recurrence in head and neck squamous cell carcinoma. American Journal of Surgery 1994; 168:381-386.

  78. Rao PH, Sreekantaiah C, Schantz SP, Chaganti RSK. Cytogenetic analysis of 11 squamous cell carcinomas of the head and neck. Cancer Genetics and Cytogenetics 1994; 77:60-64.

  79. Hughes CJ, Reed JA, Cabal R, Huvos G, Albino AP, Schantz SP. Increased expression of basic fibroblast growth factor (bFGF) in squamous carcinogenesis of the head and neck: lower incidence following smoking cessation American Journal of Surgery 1994; 168:381-386.

  80. Savage HE, Kolli V, Zhang J, Alfano RR, Sacks PG, Schantz SP. Tissue autofluorescence spectroscopy: in vivo alterations may reflect cellular proliferation SPIE Proc 1994; 2135:16-25.

  81. Benner SE, Pajak TF, Lippman SM, Schantz SP, Gallagher MI, Shenouda G, Stetz J, Hong WK. Toxicity of isotretinoin in a chemoprevention trial to prevent second primary tumors following head and neck cancer Journal of the National Cancer Institute 1994; 86:1799-1801.

  82. Lydiatt WM, Murty VVS, Davidson BJ, Xu L, Dyomina K, Sacks PG, Schantz SP, Chaganti RSK. Homozygous deletions and loss of expression of the CDKN2 occur frequently in head and neck squamous cell carcinoma cell lines but infrequently in primary tumors. Genes, Chromosomes, and Cancer 1995; 13:94-98.

  83. Garewal H, Schantz SP. Emerging role of beta-carotene and antioxidant nutrients in oral cancer prevention. Archives of Otolaryngology Head and Neck Surgery 1995; 121:141-144.

  84. Ostroff JS, Jacobsen PB, Moadel AB, Spiro RH, Kraus DH, Strong EW, Shah JP, Schantz SP. Prevalence and predictors of continued tobacco use following diagnosis of head and neck cancer. Cancer 1995; 75:569-576.

  85. Begg CB, Zhang ZF, Sun M, Herr HW, Schantz SP. Methodology for evaluating incidence of second primary cancers with application to smoking-related cancers from S.E.E.R. American Journal Epidemiology 1995; 142:653-665.

  86. Savage HE, Kolli V, Ansley J, Chandawarkar RT, Alfano RR, Schantz SP. Innate tissue fluorescence of the oral mucosa of controls and head and neck cancer patients. SPIE Proceedings 1995; 2387:2-14.

  87. Savage HE, Kolli V, Saha S, Zhang JC, Glasgold M, Sacks PF, Alfano R, Schantz SP. Development of in-vitro models to elucidate mechanisms of intrinsic cellular proliferation and differentiation models. SPIE Proceedings 1995; 2387:44-56.

  88. Kolli V, Shaha AR, Savage HE, Sacks PG, Casale MA, Schantz SP. Native cellular fluorescence can identify changes in epithelial thickness in-vivo in the upper aerodigestive tract. American Journal of Surgery 1995; 495-498. 

  89. Kolli V, Savage HE, Yao TJ, Schantz SP. Native cellular fluorescence of neoplastic upper aerodigestive mucosa Archives of Otolaryngology Head and Neck Surgery 1995; 121:1287-1292.

  90. McGuire M, Lydiatt W, Trambert R, Shaha A, Schantz S. Head and neck screening day for the community. Annals of New York Academy of Science 1995; 768: 148-162. 

  91. Demos SG, Savage HE, Heerdt A, Schantz SP, Alfano, RR. Time resolved degree of polarization for human breast tissue. Optics Communications 1996; 124: 439 - 442.

  92. Lazarus P, Steen J, Zweibel N, Fair S, Ritchie JP, Schantz SP. Relationship between p53 mutation incidence in oral cavity squamous cell carcinomas and patient tobacco use. Carcinogenesis 1996; 17: 733-739.

  93. Katz A, Ganesan S, Savage HE, Schantz SP, Alfano RR. Optical biopsy fiber based fluorescence instrumentation. SPIE Proceedings 1996; 2679: 118-123.

  94. Davis RA, Savage H, Alfano RR, Schantz SP. Influence of keratin on native cellular fluorescence of human skin. SPIE Proceedings 1996; 2679: 118-123.

  95. Sacks PG, Savage HE, Levine J, Kolli VR, Alfano RR, Schantz SP. Native cellular fluorescence identies terminal squamous differentiation of normal oral epithelial cells in culture: a potential chemopreventive biomarker. Cancer Letters 1996; 104:171-181. 

  96. Cloos J, Spitz MR, Schantz SP, Hsu TC, Zhang ZF, Tobi H, Braakhuis BJM, Snow GB. Genetic susceptibility to upper aerodigestive tract cancers. Journal of the National Cancer Institute 1996; 88:530-535.

  97. Xu L, Schantz SP, Edelstein D, Sacks PG. A simplified method for the routine culture of normal oral epithelial cells from upper aerodigestive tract mucosa. Methods in Cell Science 1996; 18:31-39.

  98. Brenner PC, Herr HW, Moore MJ, Sheinfeld J, Aprikian A, Bosl GJ, Motzer RJ, Bajorin DF, Schantz S, Fair WR, Burt M. Simultaneous retroperitoneal, thoracic, and cervical resection of postchemotherapy residual masses in patients with metastatic nonseminomatous germ cell tumors of the testis. Journal of Clinical Oncology 1996; 14:1765-1769.

  99. Kraus DH, Rosenberg DB, Davidson BJ, Shaha AR, Spiro RH, Strong EW, Schantz SP, Shah JP. Supraspinal accessory lymph node metastases in supraomohyoid neck dissection. American Journal of Surgery 1996; 172:646-649.

  100. Davidson BJ, Lydiatt WM, Abate MP, Schantz SP, Chaganti RSK. Cyclin D1 (CCND1) abnormalities correlate with risk factor exposure in head and neck squamous cell carcinoma (HNSCC). Head Neck 1996; 18:512-521.

  101. Mestre JR, Subbaramaiah K, Sacks PG, Schantz SP, Tanabe T, Inoue H, Dannenberg AJ. Retinoids suppress phorbal ester-mediated induction of cyclooxygenase-2. Cancer Research 1997; 57:1081-1086.

  102. Schantz SP, Savage HE, Sacks P, Alfano RR. Native cellular fluorescence and its application to cancer prevention. Environmental Health Perspectives 1997; 105(Suppl 4):941-944.

  103. Mestre JR, Subbaramaiah K, Sacks PG, Schantz SP, Tanabe T, Inoue H, Dannenberg AJ. Retinoids suppress epidermal growth factor-induced transcription of cyclooxygenase-2 in human oral epithelial cells. Cancer Research 1997; 57:2890-2896.

  104. Schantz SP, Zhang ZF, Spitz ML, Hsu TC. Genetic susceptibility to head and neck cancer: the interaction between nutrition and mutagen sensitivity. Laryngoscope 1997; 107:765-781.

  105. Kelley DJ, Sacks PG, Schantz SP, Ramonetti JT, Dannenberg AJ. Curcumin inhibits benzo[a] pyrene and phorbal ester-mediated induction of cyclooxygenase-2 and prostaglandin synthesis in oral epithelial cells. Carcinogenesis 1997; 18:795-799.

  106. Spitz MR, McPherson RS, Jiang H, Hsu TC, Trizna Z, Lee JJ, Lippman SM, Khuri FR, Steffen-Batey L, Chamberlain RM, Schantz SP, Hong WK. Correlates of mutagen sensitivity in patients with upper aerodigestive tract cancer. Cancer Epidemiology, Biomarkers & Prevention 1997; 6:687-692.

  107. 107. Guo Y, Ho PP, Savage H, Harris D, Sacks P, Schantz S, Liu F, Zhadin N, Alfano RR. Second-harmonic tomography of tissues. Optics Letters 1997; 22:1323- 1325.

  108. Park JY, Ren Q, Schantz SP, Harwick RD, Muscat JE, Ritchie JP, Miller AS, Lazarus P. CYP1A1 and GSTM1 polymorphisms, tobacco use, and oral cancer risk. Cancer Epidemiology Biomarkers & Prevention 1997; 6:791-799.

  109. Zhang JC, Sacks PG, Savage HE, Delohery T, Schantz SP. Innate cellular fluorescence reflects alterations in cellular proliferation. Lasers in Surgery and Medicine 1997; 20:319-331. 

  110. Yu G, Ostroff JS, Zhang ZF, Tang J, Schantz SP. Smoking history and cancer patient survival: A hospital cancer registry study. Cancer Detection and Prevention 1997; 21:497-509.

  111. Schantz SP, Vaidya SG. Green tea and leukoplakia. American Journal of Surgery. American Journal of Surgery 1997; 174:552-555

  112. Demos SG, Savage H, Heerdt AS, Schantz SP, Alfano RR. Temporal polarization preservation in human breast tissue - a method for optical imaging. SPEI Proceedings 1997; 2695:40-43.

  113. Demos SG, Papadopoulos AJ, Savage H, Heerdt AS, Schantz SP, Alfano RR. Polarization filter for biomedical tissue optical imaging. Photochemistry and Photobiology 1997; 66: 821-825.

  114. Yang CS, Chen L, Lee MJ, Balentine D, Kuo MC, Schantz SP. Blood and urine levels of tea polyphenols after ingestion of different amounts of tea by human volunteers Cancer Epidemiology Biomarkers & Prevention 1998; 7:351-354.

  115. Lydiatt WM, Davidson BJ, Schantz SP, Chaganti RSK. 9p21 deletion correlates with recurrence in head and neck cancer. Head and Neck 1998; 20:113-118.

  116. Lydiatt WM, Anderson PE, Bazzana T, Casale M, Hughes CJ, Huvos AG, Lydiatt DD, Schantz SP. Molecular support for field cancerization in the head and neck. Cancer 1998; 82:1376-1380. 

  117. Cordeiro PG, Bacilious N, Schantz SP, Spiro R. The radial forearm osteocutaneous “sandwich” free flap for reconstruction of the bilateral subtotal maxillectomy defect. Annals of Plastic Surgery 1998; 40:397-402.

  118. Khafif A, Schantz SP, Chou TC, Edelstein D, Sacks PG. Quantitation of chemopreventive synergism between (-)-epigallochatechin-3-gallate and curcumin in normal, premalignant, and malignant human oral epithelial cells. Carcinogenesis 1998; 19:419-424.

  119. Guo Y, Liu F, Wang QZ, Zhadin N, Ho PP, Savage H, Harris D, Sacks P, Schantz SP, Alfano RR. Savage H, Liu F, Schantz S, Ho P, Alfano R. Second harmonic and two photon fluorescence histology of tissues. SPIE Proceedings 1998; 3250:210-212. 

  120. Yang Y, Liu CH, Savage HE, Schantz Sp, Alfano RR. Optical fluorescence and Raman biopsy of squamous cell carcinoma from the head and neck. SPIE Proceedings 1998; 3250:68-71.

  121. Katz A, Savage HE, Zeng F, Rome J, Tang GC, Harris D, Koutcher J, Schantz SP, Alfano RR. Fluorescence ratio mapping system for tissue diagnosis. SPIE Proceedings 1998;3250:64-67.

  122. Liu F, Shan YX, Savage H, Heerdt AS, Schantz S, Celmer E, Alfano RR. Measurements of effective group index of refraction and scattering mean free path of normal and malignant human breast tissues using ultrafast optical techniques. Proceedings of the Optical Society of America 1998; 2:376-378.

  123. Spingarn A, Sacks PG, Kelley D, Dannenberg A, Schantz SP. Synergistic effects of 13-cis retinoic acid cascade inhibitors on growth of head and neck squamous cell carcinoma in vitro. Otolaryngology and Head and Neck Surgery 1998; 118:159-164. 

  124. Friedlander PL, Schantz SP, Shaha AR, Yu GP, Shah JP. Squamous cell carcinoma of the oral tongue in young patients: A matched pair analysis. Head and Neck. 1998; 20:363-368.

  125. Khafif A, Schantz SP, Sacks PG. Green tea regulates cell cycle progression in oral leukoplaka. Head and Neck 1998; 20:528-534.

  126. Schantz SP, Kolli VK, Savage HE, Yu G, Shah JP, Harris DE, Katz A, Alfano RR. Huvos AG. In-vivo native cellular fluorescence and histologic characteristics of head and neck cancer. Clinical Cancer Research 1998; 4:1177-1182.

  127. Harrison LB, Raben A, Pfister DG, Zelefsky M, Strong E, Shah JP, Spiro RH, Shaha A, Kraus DH, Schantz SP, Carper E, Bodansky B, White C, Bosl G. A prospective phase II trial of concomitant chemotherapy and radiotherapy with delayed accelerated fractionation in unresectable tumors of the head and neck. Head and Neck 1998; 20:497-503.

  128. Carew JF, Federoff H, Halterman M, Kraus DH, Savage H, Sacks PG, Schantz SP, Shah JP, Fong Y. Efficient gene transfer to human squamous cell carcinomas by the Herpes Simplex Virus Type 1 amplicon vector. American Journal of Surgery 1998; 176:404-408.

  129. Ganesan S, Sacks PG, Yang Y, Katz A, Al-Rawi M, Schantz SP, Alfano RR. Native cellular spectroscopy of normal and malignant epithelial cells. Cancer BioChemistry BioPhysics 1998; 16:365-373.

  130. Lazarus P, Sheikh SN, Ren Q, Schantz S, Stern J, Richie JP, Park JP. p53 but not p16 mutations in oral squamous cell carcinomas are associated with specific CYP1A1 and GSTM1 polymorphic genotypes and patient tobacco use. Carcinogenesis 1998; 19:509-514.

  131. Spitz MR, Lippman SM, Jiang H, Lee J, Khuri F, Jsu T, Trizna Z, Schantz S, Benner S, Hong W. Mutagen sensitivity as a precictor o ftumor recurrence in patients with cancer of the upper aerodigestive tract. Journal of the National Cancer Institute 1998; 90:243-245.

  132. Harrison LB, Raben A, Pfister DG, Zelefsky M, Strong E, Shah JP, Spiro RH, Shaha A, Kraus DH, Schantz SP, Carper E, Bodansky B, White C, Bosl G. A prospective phase II trial of concomitant chemotherapy and radiotherapy with delayed accelerated fractionation in unresectable tumors of the head and neck Head and Neck 1998; 20:497-503.

  133. Guo Y, Savage HE, Liu F, Schantz SP, Ho PP, Alfano RR. Subsurface structure of tissues investigated by noninvasive optical second harmonic tomography. Proceedings National Academy of Sciences USA 1999; 96:10854-10856.

  134. Downey RJ, Friedlander P, Groeger J, Kraus D, Schantz SP, Spiro R, Strong E, Shaha A, Shah JP. Critical outcomes in the severely ill head and neck patient. Critical Care Med 1999; 27:95-97. 

  135. Ostroff JS, Jay JL, Schantz SP, Maher MM. A survey of smoking status and cancer risk perceptions among participants attending a hospital-based head and neck screening program. Psychology and Health 2000; 14:979-990.

  136. Park JY, Schantz SP, Stern JC, Kaur T, Alvi A, Lazarus P. Association between glutathione-S-transferase genetic polymorphisms and oral cancer risk. Pharmacogenetics 1999; 9:497-504. 

  137. Yu GP, Zhang ZF, Hsu TC, Spitz MR, Schantz SP. Family history of cancer mutagen sensitivity, and increased risk of head and neck cancer: Cancer Letters 1999; 146:93-101.

  138. Zhang ZF, Morganstern H, Spitz MR, Tashkin D, Marshall JR, Hsu TC, Schantz SP. Marijuana use and increased risk of squamous cell carcinoma of the head and neck: A case-control study. Cancer Epidemiology Biomarkers and Prevention 1999; 8:1071-1078. 

  139. Katz A, Savage HE, Zeng F, Rome J, Schantz SP, McCormick SA, Cocker RS, Alfano RR. Ultraviolet 2-D fluorescence mapping system for the imaging of head and neck tumors. SPEI Proceedings 2000; 3917:146-149.

  140. Huang Q, Schantz SP, Rao PH, Mo J, McCormick SA, Chaganti RSK. Improving degenerate oligonucleotide primed PCR-comparative genomic hybridization for analysis of DNA copy number changes in tumors. Genes Chromosomes and Cancer 2000; 28:395-403.

  141. Schantz SP, Huang Q, Shah K, Murty VVVS, Hsu TC, Yu GP, Anderson PE, Huvos AG, Chaganti RSK. Mutagen-sensitivity and environmental exposures as contributing causes of chromosome 3p losses in head and neck cancer. Carcinogenesis 2000; 21:1239-1246.

  142. Zhang ZF, Morganstern H, Spitz MR, Tashkin DP, Marshall JR, Hsu TC, Schantz SP. Environmental tobacco smoke and risk of head and neck squamous cell carcinoma. Cancer Epidemiology Biomarkers and Prevention 2000; 9:1043-1049.

  143. Park JY, Muscat JE, Kaur T, Schantz SP, Stern JC, Richie JP, Lazarus P. Comparison of GSTM polymorphisms and risk for oral cancer between African-Americans and Caucasians. Pharmacogenetics 2000; 10:123 -131.

  144. Yoo HJ, Sepkovic DW, Bradlow L, Yu GP, Sirilan HV, Schantz, SP. Estrogen metabolism as a risk factor for head and neck cancer. Otolaryngology Head and Neck Surgery 2001; 124:241 – 247.

  145. Liu S, Park JY, Schantz SP, Stern J, Lazarus P. Elucidation of CYP21E1 5’ regulatory RsaI/Pstl allelic variants and their role in risk for oral cancer. Oral Oncology 2001; 437-445.

  146. Zheng Z, Guillemette C, Park JY, Schantz SP, Lazarus P. The tobacco carcinogen-detoxifying enzyme UGT1A7 and its association with orolaryngeal cancer risk in Caucasian and African Americans. Journal National Cancer Institute 2001; 93(18):1411-8. 

  147. Gayen SK, Alrubaiee M, Savage H, Schantz SP, Alfano RR. Parotid gland tissues investigated by picosecond time-gat ed and optical spectroscopic imaging techniques. IEEE Journal on Selected Topics in Quantum electronics. 2001; 7:906 – 911. 

  148. Sandoval S, Schantz SP, Posey D, Swift M. Parotid and thyroid gland cancers in patients with ataxia-telangiectasia. Pediatric Oncology Hematology 2001; 18:485-495.

  149. Schantz SP, Yu GP. Head and neck incidence trends in young Americans, 1973 – 1997, with a special analysis for tongue cancer. Archives of Otolaryngology and Head and Neck Surgery. Archives of Otolaryngology and Head and Neck Surgery 2002; 128:268 - 274.

  150. Katz A, Savage HE, Schantz SP, McCormick SA, Alfano RR. Noninvasive native fluorescence imaging of head and neck tumors. Technology in Cancer Research and Treatment 2002; 1:9 -17.

  151. Huang Q, Yu GP, McCormick SA, Mo J, Datta B, Mahimkar M, Lazarus P, Schaffer AA, Desper R, Schantz SP. Genetic differences detected by comparative genomic hybridization in head and neck squamous cell carcinomas from different tumor sites: Construction of oncogenetic trees for tumor progression. Genes Chromosomes and Cancer 2002; 34:224 – 233.

  152. Elahi A, Bendally J, Zheng Z, Schantz SP, Richie JP, Lazarus P. UGT1A10 polymorphisms and potential association with risk for oropharyngeal cancer . Cancer 2003; 98:872-880.

  153. Park J, Schantz SP, Lazarus P. Epoxide hydrolase genotype and orolaryngeal cancer risk: Interaction with GSTM1 genotype. Oral Oncology 2003; 39:483 - 490.

  154. Pitman MJ, Rosenthal JM, Yu G, McCormick S, Savage H, Schantz SP. Native cellular fluorescence of thyroid nodules. Otolaryngology Head and Neck Surgery 2004; 131:623-627.

  155. M Naydich, M Ghesani, S Malamud, S Schantz: Incidental Findings on Whole Body FDG PET Scans are Frequently Due To Malignant or Premalianant Conditions," Journal of Nuclear Medicine.( submitted for publication). 

  156. Tadi K, Chang Y, Ashok BT, Chen Y, Moscatello A, Schaefer S, Schantz SP, Policastro AJ, Geliebter J, Tiwari R. 3,3’-Diindolylmethane, a cruciferous vegetable derived synthetic anti-proliferative compound in thyroid disease. Biochemical and Biophysical Research Communications 2005; 337:1019-1025.

  157. Frank DK, Hu KS, Culliney BE, Persky MS, Nussbaum M, Schantz SP, Malamud SC, Holliday RA, Khorsandi AS, Sessions RB, Harrison LB. Planned neck dissection after concomitant radiochemotherapy for advanced head and neck cancer. Laryngoscope 2005; 115:1015-1020.

  158. Huang, Q.; Sacks, P; Mo, J; McCormick, S; Iacob; Guo, L; Schaefer, S; Schantz, SP. A simple method for fixation and microdissection of frozen fresh tissue sections for molecular cytogenetic analysis of cancers. Biotechnic and Histochemistry 2005; 80:147-156.

  159. Suriano R, Lin Y, Ashok BT, Schaefer SD, Schantz SP, Geliebter J, Tiwari RK. A pilot study using SELDI-TOF-MS based proteomic profile for the identification of diagnostic biomarkers of thyroid proliferative diseases. Journal of Proteomic Research 2006; 5:856-861.

  160. Chan E, Schantz SP. A hormonal association between estrogen metabolism and proliferative thyroid disease. Otolaryngology and Head and Neck Surgery 2006; 134:893-900.

  161. Yu G, Schantz SP, Neugat AI, Zhang ZF. Incidences and trends of second cancers in female breast cancer patients: A fixed inception cohort analysis. Cancer Causes and Prevention 2006; 17:411-420.

Invited Articles

  1. Schantz SP. "Compartmentalization" in head and neck cancer. Head and Neck Surgery 9:263-264, 1987. Editorial

  2. Schantz SP. The biologic staging of head and neck cancer. Cancer Bulletin 39:103-109, 1987.

  3. Lotan R, Kim JS, Maaroui M, Schantz SP, Hong WK. Vitamin A retinoids, and the prevention and treatment of head and neck cancer. Cancer Bulletin 39:93-98, 1987.

  4. Schantz SP, Goepfert H. The biology of head and neck cancer. An editorial. Cancer Bulletin 39:73-75, 1987.

  5. Schantz SP, Guillamondegui OM. Developing perspectives in head and neck tumor immunology. Problems in General Surgery 5:99-112, 1988.

  6. Goepfert H, Schantz SP. The biologic staging of head and neck cancer (Editorial). Head Neck 12-291-292, 1990.

  7. Schantz SP. Experimental head and neck oncology. Current Opinion in Oncology 3:500-507, 1991.

  8. Schantz SP. Experimental head and neck oncology. Current Opinion in Oncology 2:546 551, 1990.

  9. Hsu TC, Spitz MR, Schantz SP. Mutagen sensitivity: A biological marker of cancer susceptibility. Cancer Epidemiology, Biomarkers, and Prevention 1:83-89, 1991.

  10. Schantz SP, Clayman GL, Dimery I, Morice R. Combination interleukin-2 and interferon-alpha in head and neck cancer patients. Cancer Bulletin 43:133-145, 1991.

  11. Trizna Z, Schantz SP. Hereditary and environmental factors associated with risk and progression of head and neck cancer. Otolaryngologic Clinics of North America 25:1089-1103, 1992.

  12. Schantz SP. Experimental head and neck oncology. Current Opinion in Oncology 4:478-484, 1992.

  13. Schantz SP, Shah JP. Chemoprevention and head and neck cancer. Editorial. Oncology 6:68, 1992.

  14. Schantz SP. Carcinogenesis, biologic markers and prevention. Current Opinion in Oncology 5:483-490, 1993.

  15. Shah JP, Medina JE, Shaha AR, Schantz SP, Marti JR. Cervical lymph node metastasis. Current Problems in Surgery 30:273-344, 1993.

  16. Schantz SP. Chemoprevention: The relevance of neoplasias of the upper aerodigestive tract. Journal of Cellular Biochemistry 17F:18-27, 1993.

  17. Schantz SP, Alfano RR. Tissue autofluorescence as an intermediate endpoint in chemoprevention trials. Journal of Cellular Biochemistry 17F:199-205, 1993.

  18. Schantz SP, Alfano RR. Assays for markers of chronic carcinogen exposure and their modulation by chemopreventive agents. (a session overview). Journal of Cellular Biochemistry 17F:118, 1993.

  19. Schantz SP, Hong WK, Boone CW, Kelloff GJ. Strategy for design of clinical trials of chemopreventive agents. Journal of Cellular Biochemisty Supplement 17F:299-301, 1993.

  20. Schantz SP, Hong WK, Boone CW, Kelloff GJ (Eds) Chemoprevention of premalignant lesions of the upper aerodigestive tract. Journal of Cellular Biochemistry. Supplement 17F, 1993.

  21. Schantz SP. Biologic markers, cellular differentiation, and metastatic head and neck cancer. European Archives of Oto-Rhino-Laryngology 250:424-429, 1993.

  22. Schantz SP. Biologic staging 1993. Current Opinion in Otolaryngology Head and Neck Surgery 1:107-113, 1993.

  23. Schantz SP. Head and neck oncology research. Current Opinion in Oncology 6:265-271, 1994.

  24. Schantz SP. Chemoprevention of tobacco-Induced neoplasms. J Smoking Related Disorders 5S:29-35, 1994.

  25. Schantz SP. Basic science advances in head and neck oncology. The past decade. Seminars in Surgical Oncology 11:272-279, 1995.

  26. Lydiatt WL, Schantz SP. The biological staging of head and neck cancer and its implication in therapy. Cancer Metastasis Reviews 15:11-25, 1996.

  27. Berwick M, Schantz SP. The chemoprevention of aerodigestive cancer. Cancer Mestastasis Reviews 16:329-347, 1997.

  28. Schantz SP, Ostroff JS. Novel approaches to the prevention of head and neck cancer. Proceedings of the Society for Experimental Medicine in Biology 2:275-283, 1997.

Books & Chapters

  1. Lotan R, Schantz SP, Hong WK. The use of retinoids in head and neck cancer. In: Jacobs C, ed. Cancer of the Head and Neck. Boston: Martinus Nijhoff, 1987:177-191.

  2. Savage HE, Schantz SP, Sacks PG, Birdsall HH, Rossen RD. Serum antibodies from head and neck cancer patients provide molecular probes to identify and characterize antigens in autologous and allogeneic tumor cells. In: Wolf GT, Carey TE, eds. Head and Neck Oncology Research. Amsterdam: Kugler Publications, 1988:109-119.

  3. Schantz SP, Brock WA, Taylor DL, Dekmezian R, Meistrich ML. Growth modulation of head and neck cancer by autologous host cells: A model system. In: Wolf GT, Carey TE, eds. Head and Neck Oncology Research. Amsterdam: Kugler Publications, 1988:99-107.

  4. Schantz SP, Shillitoe EJ, Brown B, Campbell B. Natural killer activity and head and neck cancer: A clinical assessment (abstract). In: Hickey RC, ed. Yearbook of Cancer. Houston: Year Book Medical Publishers, 1988:45-46.

  5. Schantz SP, Savage HE, Lee NK. Head and neck tumor immunology. II. Humoral immunity. In: Jacobs C, ed. Head and Neck Oncology III. Norvall, MA: Kluwer Academic Publishers, 1990:243-264.

  6. Parkinson DR, Schantz SP. The immunobiologic therapy of head and neck cancer. In Snow G, Clark J, eds. Multimodality Therapy for Head and Neck Cancer, George Thieme Verlag, 1992:147-159.

  7. Spitz MR, Hsu TC, Schantz SP. Genetic and environmental interactions as risks for aerodigestive cancers. In: Newell GR, Hong WK eds. Biology and Prevention of Aerodigestive Cancers. New York: Plenum Press 1992.

  8. Schantz SP, Lavedan P, Savage HE. The interaction of humeral and cellular immunity. Dr. Brian McCabe ed. 3rd International Academic Conference on Immunobiology in Otology, Rhinology and Laryngology. Amsterdam: Kugler Publications,1992. 

  9. Schantz SP, Harrison L, Hong WK. Tumors of the nasal cavity and paranasal sinuses, nasopharynx, oral cavity, and oropharynx. In DeVita VT, Hellman S, Rosenberg SA, eds. Cancer: Principles and Practices of Oncology. J.B. Lippincott Co, Philadelphia, PA, 1993:574-673.

  10. Schantz, SP. Biologic response modifiers and host response. In: Johnson JT, Didolkar MS, eds. Head and Neck Cancer Vol. III, Amsterdam: Excepta Medica, 1993:113-117.

  11. Schantz SP. The challenge of tumor markers. In: Johnson JT, Shah JP, eds. Proceedings of the Fourth International Conference on Head and Neck Cancer , Volume IV. The Society of Head and Neck Surgeons and The American Society of Head and Neck Surgery, 1996: 479-486.

  12. Schantz SP, Lee NK. Tobacco carcinogenesis and head and neck cancer. In: Werner JA, Lippert BM, Rudert HH, eds. Head and Neck Cancer: Advances in Basic Research. Excerpta Medica, Amsterdam, 1996: 9-21.

  13. Schantz SP, Harrison LB, Forastiere AA. Tumors of the nasal cavity and paranasal sinuses,, nasopharynx, oral cavity, and oropharynx. In DeVita VT, Hellman S, Rosenberg SA, eds. Cancer: Principles and Practices of Oncology. J.B. Lippincott Co, Philadelphia, PA, 1997:741-802.

  14. Schantz SP, Andersen PE. Post-treatment follow up of the head and neck cancer patient. In: Johnson FL, Virgo KS, eds. Cancer Patient Follow-Up. Mosby-Year Book, Inc. 1997:57-64. 

  15. Guo Y, Liu F, Wang QZ, Savage HE, Zhadin N, Ho PP, Schantz SP, Alfano RR. Nonlinear optical histological spectroscopy and imaging of biological tissues. In: Fugimoto JG, Patterson MS, eds. Advances in Optical Imaging and Photon Migration. Optical Society of America, 1998.

  16. Trizna Z, Schantz SP. Tobacco-related cancers of the respiratory and upper aerodigestive tract. In: Foulkes W, Hodgson S, eds. Inherited Susceptibility to Cancer: Clinical, Predictive, and Ethical Perspectives. Cambridge University Press, Cambridge, 1998.

  17. Schantz SP, Harrison LB, Forastiere AA. Tumors of the nasal cavity and paranasal sinuses,, nasopharynx, oral cavity, and oropharynx. In DeVita VT, Hellman S, Rosenberg SA, eds. Cancer: Principles and Practices of Oncology. J.B. Lippincott Co, Philadelphia, PA, 2001:797-861.

  18. Moadel AB, Ostoff JS, Schantz SP. Site-specific psychological issues: Head and neck cancer. In: Holland JC, Massie MJ, eds. Handbook of Psycho-Oncology: Psychological Care of the Patient with Cancer (in-press).

  19. Schantz SP, Yu GP. The epidemiology of head and neck cancer. In: Wenig B, Abemayor E, Fu YS, Wenig B, eds. Pathology of the Head and Neck with Clinical Pathologic Correlations. Churchill Livingstone, New York (in-press).

Abstracts

  1. Schantz SP, Poisson L, Nishioka K, Romsdahl MM, Byers RM. Natural killer cell activity and head and neck cancer. Proceedings of the American Association for Cancer Research 1985; 26:308.

  2. Schantz SP, Brown B, Schwartz B. NK cell activity, prognosis, and head and neck cancer. Proceedings of the American Society for Clinical Oncology 1986; 5:223.

  3. Schantz SP, Peters L. Patterns of recurrence from head and neck cancer: An immunologic perspective. American Journal of Clinical Oncology 1987 10:114.

  4. Schantz SP, Ordonez N. Natural killer cell activity predicts metastases from poorly differentiated head and neck cancer. Proceedings of the American Association for Cancer Research 1988; 29:374.

  5. Schantz SP, Lui FJ, Taylor D, Beddingfield N, Weber RS. The relationship between circulating immunoglobulin A and cellular immunity in the head and neck cancer patient. American Journal of Clinical Pathology 1988; 90:514.

  6. Schantz SP, Savage HE, Hong WS, Rossen RD. The quantitation of circulating immune complexes predicts head and neck cancer response to induction chemotherapy. Proceedings of the American Society of Clinical Oncology 1988; 7:149.

  7. Riley LB, Pellis NR, Itoh K, Schantz SP, Freedman RS, Parkinson DR, Balch CB. Cancer patients have two distinct inhibitors of LAK induction. Proceedings of the American Association of Cancer Research 1989; 30:366.

  8. Spitz MR, Fueger JJ, Hsu TC, Schantz SP, Newell GR. Chromosome sensitivity to bleomycin-induced metagenesis in patients with upper aerodigestive cancers. Proceedings of the American Association of Cancer Research 1989; 30:314.

  9. Racz T, Van N, Sacks PG, Ordonez N, Schantz SP. The differential sensitivity of head and neck cancers to non-major histocompatibility restricted killer cell lysis. Proceedings of the American Association of Cancer Research 1989; 30:338.

  10. Schantz SP, Savage H, Young G, Hong WK. C1q binding macromolecules and survival in head and neck cancer patients. Proceedings of the American Society of Clinical Oncology 1989; 8:170.

  11. Hong WK, Lippman SM, Itri L, Karp D, Lee JS, Byers RM, Kramer A, Schantz S, Lotan R, Dimery I, Peters L, Brown B, Goepfert H. Prevention of second malignant tumors (SMT) in head and neck cancer with 13- cis-retinoic acid (13-CRA): Double-blind randomized trial. Proceedings of the American Society of Clinical Oncology 1990; 9:171.

  12. Sacks PG, Schantz SP. A multicellular tumor spheroid model to study natural immune function. Proceedings of the American Association of Cancer Research 1990; 31:248.

  13. Clayman GL, Taylor D, Savage HE, Schantz SP. Autologous serum modulation in the effector phase of natural killer cells and LAK cells: An in-vitro model for immunomodulation. Otolaryngology Head and Neck Surgery 1990; 103:208.

  14. Sen P, Schantz SP, Shillitoe E. Chromosomal anomalies in lymphoblastoid cell lines from head and neck cancer patients with multiple tremors. Proceedings of the American Association of Cancer Research 1991; 32:31.

  15. Lavedan P, Savage HE, Taylor DL, Schantz SP. The interaction of cellular and humoral immunity in head and neck cancer patients. Proceedings of the American Association of Cancer Research 1991; 32:236.

  16. Sacks PG, Taylor DL, Schantz SP. Retinoic acid modulation of immune function in a multicellular tumor spheroid model for head and neck cancer. Proceedings of the American Association of Cancer Research 1991; 32:252.

  17. Pfister DG, Harrison L, Strong E, Shah J, Spiro R, Fass D, Kraus D, Schantz S, Weiss M, Wong R, Bosl GJ. Tongue/larynx preservation in advanced oropharynx cancer: Results with induction chemotherapy and radiation. Proceedings of the American Society of Clinical Oncology 1992; 11:A776.

  18. Sacks PG, Ordonez N, Soliman F, Taylor D, Schantz SP. Immune killing in a multicellular tumor spheroid (MTS) model for squamous carcinoma is potentiated by retinoic acid (RA). Proceedings of the American Association for Cancer Research 1993; 34:492.

  19. Xu L, Davidson BJ, Sacks PG, Schantz SP, Garin-Chesa P, Chaganti RSK. 11q13 amplification and p53 mutations in head and neck squamous cell carcinoma. Proceedings of the American Association for Cancer Research 1993; 34:501. 

  20. Davidson BJ, Sacks PG, Xu L, Schantz SP, Chaganti RSJ. -KBp65 is coamplified and rearranged in head and neck squamous cell carcinoma. Proceedings of the American Association for Cancer Research 1993; 34:528.

  21. Davidson B, Sacks PG, Schantz SP, Chaganti R. Overexpression and amplification of a cell cycle regulating protein is common in head and neck cancer. Otolaryngology Head and Neck Surgery 1993; 109:236.

  22. Davidson B, Abate M, Chaganti R, Schantz S. Cyclin D1 amplification, risk factors and clinico-pathologic presentation in head and neck cancer. Otolaryngology Head and Neck Surgery 1993; 109:248.

  23. Schantz SP, Zhang J, Sacks P, Alfano RR. The relationship of aerodigestive mucosal diseases to autofluorescence profiles. Proceeding of the International Society for Optical Engineering (in press).

  24. Sturgis EM, Sacks P, Masui H, Mendelsohn J, Schantz SP. The effects of anti-epidermal growth factor receptor antibody 528 on the proliferation and differentiation of head and neck cancer. Otolaryngology Head and Neck Surgery 1993; 109:238.

  25. Pfister D, Harrison L, Kraus D, Shah J, Spiro R, Armstrong J, Zelefsky M, Schantz S, Weiss M, Kuhel W, Bosl G,Strong E. Larynx preservation (CP): Feasibility and preliminary efficacy of concomitant cisplatin (C) and delayed hyperfractionated (DHF) radiation (RT) after initial c-based chemotherapy (CT). Proceedings of the American Society of Clinical Oncology 1994; 13:292.

  26. Zhang JC, Sacks PG, Savage HE, Schantz SP. Tissue autofluorescent identification of in-vitro cellular proliferation: a potential chemprevention biomarker. Proceedings American Association for Cancer Research 1994; 35:620.

  27. Harris LB, Zelefsky MB, Pfister DG, Carper E, Bodansky B. Schantz SP, Silver-Segundo B, Thaler H, Polyak T, Portenoy RK. Detailed quality of life assessment after radiation therapy for squamous cell cancer of the larynx, oropharynx, and nasopharynx. A.S.T.R.O.

  28. Saha S, Savage HE, Pinto JT, Qiao CH, Sacks PG, Schantz SP. Autofluorescence changes in progressive esophageal neoplasia in the Sprague-Dawley rat as a model for field cancerization of upper aerodigestive tract mucosa. Head and Neck 1994; 16:510.

  29. Saha S, Hughes CJ, Cabal R, Pinto JT, Savage HE, Reed JA, Schantz SP, Albino AP. Enhanced utility of an in-vivo field cancerization model through in-situ hybridization analysis Head and Neck 1994; 16:483.

  30. Ansley JF, Savage HE, Schantz SP. Autofluorescence profiles of normal oral cavity mucosa. Head and Neck 1994; 16:488.

  31. Kolli VR, Savage HE, Schantz SP. In vivo tissue autofluorescence of neoplastic aerodigestive tract mucosa. Head and Neck 1994; 16:488.

  32. Lo Presti RT, Savage HE, Sacks PG, Schantz SP. Cytokeratins: Detection of these markers of differentiation using autofluorescence scanning. Head and Neck 1994; 16:489.

  33. Davidson BJ, Zheng J, Sacks PG, Schantz SP. Oncogene directed treatment of a head and neck squamous cell carcinoma (HNSCC) cell line with cyclin D1 (CCND1) amplification. Head and Neck 1994; 16:500. 

  34. Davidson BJ, Lydiatt WM, Abate MP, Schantz SP. Cyclin D1 (CCND1) amplification is associated with tobacco exposure. Head and Neck 1994; 16:500.

  35. Zhang ZF, Sptiz MR, Harlap S, Trambert R, Sun M, Begg CB, Schantz SP. Dietary factors, smoking, drinking, and risk of head and neck cancer. Head and Neck 1994; 16:479.

  36. Lydiatt WM, Schantz SP. Loss of heterozygosity in head and neck tumors is more frequent in patients without a history of tobacco exposure. Head and Neck 1994; 16:476.

  37. Abate MP, Trambert RS, Jacobsen PB, Ostroff JS, Schantz SP. Knowledge of smoking-related risks among newly diagnosed patients with squamous cell carcinoma of the upper aerodigestive tract. Head and Neck 1994; 16:516.

  38. Ostroff JS, Jacobsen PB, Schantz SP. Prevalence and predictors of combined tobacco use following diagnosis of head and neck cancer. Head and Neck 1994; 16:516.

  39. Spingarn A, Sacks PG, Schantz SP. 13-cis retinoic acid potentiates growth inhibition of arachidonic acid cascade inhibitors on human head and neck squamous cell carcinoma in vitro. Head and Neck 1994; 16:497.

  40. Xu L, Sacks PG, Schantz SP. Comparison of conditions for the culture of normal human epithelia of the upper aerodigestive tract. Head and Neck 1994; 16:478.

  41. Savage HE, Sacks PG, Kolli V, Harris D, Schantz SP. Intrinsic tissue autofluorescence can identify retinoic acid induced changes in a multicellular tumor spheroid (MTS) model. Head and Neck 1994; 16:495.

  42. Yellin SA, Davidson BJ, Pinto JT, Sacks PG, Qiao C, Schantz SP. Relationship of glutathione and glutathione-S-tranferase to cisplatin sensitivity in human head and neck squamous carcinoma cell lines. Head and Neck 1994; 16:507.

  43. Lydiatt WM, Schantz SP. Head and neck tumors occurring in patients without a history of tobacco exposure have a higher frequency of loss of heterozygosity than tobacco using patients. Head and Neck 1994; 16:476.

  44. Parisier SC, Goldrich MS, Savage H, Schantz SP. Intrinsic cellular and tissue fluorescence as a methodology for differentiating cholesteotoma from auricular epithelia. Otolaryngology Head and Neck Surgery 1994; 111:126.

  45. Lydiatt WM, Davidson BJ, Schantz SP. Deletion of 9p occurs frequently in squamous cell carcinoma of the head and neck and is located between IFN and D9519 at 9p21. Otolaryngology Head and Neck Surgery 1994; 111:63.

  46. Spingarn AA, Sacks PG, Schantz SP. Synergistic effects of retinoids and arachidonic acid cascade inhibitors on growth of head and neck squamous cell carcinoma in vitro. Otolaryngology Head and Neck Surgery 1994; 111:74.

  47. Davidson BJ, Zhang JC, Sacks PG, Schantz SP. Antisense oligonucleotide treatment of head and neck cancer. Otolaryngology Head and Neck Surgery 1994; 111:82.

  48. Spitz MR, Trizna Z, Hsu TC, Schantz SP. Second malignant tumors in patients with upper aerodigestive tract cancer. Head and Neck 1994; 16:480.

  49. Kolli VR, Savage HE, Schantz SP. In vivo native cellular fluorescence can identify changes in oral mucosal thickness. Proceedings of the American Association for Cancer Research (in press).

  50. Sacks PG, Savage HE, Levine J, Kolli V, Schantz SP. Tissue autofluorescent identification of in-vitro epithelial differentiation: a potential chemopreventive biomarker. Proceedings of the American Association for Cancer Research 36:588, 1995.

  51. Kelley D, Sacks PG, Ramonetti JT, Schantz SP, Dannenberg AJ. Curcumin inhibits prostaglandin synthesis and cyclooxygenase-2 expression in human oral epithelial cells. Proceedings of the American Association of Cancer Research 1996; 37:598.

  52. Kelley D, Sacks PG, Schantz SP, Dannenberg AJ. Benzo(a)pyrene (B[a]P) up-regulates cyclooxygenase-2 and prostaglandin synthesis in human oral epithelial cells. Proceedings of the American Association of Cancer Research 1996; 37:131.

  53. Lazarus P, Ren Q, Strudwick S, Muscat J, Stern J, Schantz S. GSTM1 and CYP1A1 polymorphisms and oral cavity cancer risk. Proceedings of the American Association of Cancer Research 1996; 37:107.

  54. Mestre JR, Subbaramaiah K, Sacks PG, Schantz SP, Tanabe T, Inoue H, Jetten AM, Dannenberg AJ. Retinoids suppress phorbol ester-mediated induction of cyclooxygenase-2 in human oral epithelial cells. Proceedings of the American Association of Cancer Research 1997; 38:174.

  55. Sacks PG, Khafif A, Al-Rawi M, Dannenberg AJ, Schantz SP. Antiproliferative effects of curcumin and (-)-epigallocatechin-3-gallate (EGCG) on normal and premalignant human oral epithelial cells. Proceedings of the American Association of Cancer Research 1997; 38:261. 

  56. Mestre JR, Subbaramaiah JR, Sacks PG, Schantz SP, Tanabe T, Inoue H, Dannenberg AJ. Retinoids suppress epidermal growth factor-mediated induction of cyclooxygenase-2 in human oral epithelial cells. Proceedings of the American Association of Cancer Research 1997; 38:261.

  57. Michaluart PM, Mestre JR, Subbaramaiah K, Schantz SP, Grunberger D, Carothers AM, Dannenberg AJ. Caffeic acid phenethyl ester (CAPE) inhibits phorbol ester-mediated induction of cyclooxygenase-2 in human oral epithelial cells. Proceedings of the American Association of Cancer Research 1997; 38:363.

  58. Caruana SM, Schantz SP, Sacks PG, Chaganti RSK. Comparative analysis of primary and metastatic tumor mRNA in head and neck squamous carcinoma using differential display. Proceedings of the American Association of Cancer Research 1997; 38:545.

  59. Park J, Kaur T, Schantz SP, Harwick R, Stern J, Muscat J, Lazarus P. Interethnic variability and genetic linkage in GSTM1 and GSTM3 polymorphic frequencies. Proceedings of the American Association of Cancer Research 1997; 38:213.

  60. Khafif A, Kim J, Schantz SP, Sacks PG. Curcumin-induced growth inhibition of oral cancer cells involves multiple cell-cycle checkpoints. Proceedings of the American Association of Cancer Research 1999; 39:19.

  61. Park J, Ren Q, Schantz SP, Stern J, Richie JP, Sheikh SN, Lazarus P. p53 mutations in oral tumors are associated with specific CYP1A1 and GSTM1 polymorphic genotypes and patient tobacco use. Proceedings of the American Association of Cancer Research 1999; 39:183.

  62. Michaluart P, Subbaramaiah K, Carothers A, Grunberger D, Mestre JR, Sacks PG, Schantz SP, Masferrer JL, Kobolt CB, Zweifel BS, Tanabe T, Dannenberg AJ. Caffeic acid phenethyl ester (CAPE) inhibits phorbol ester-mediated induction of prostaglandin synthesis in human oral epithelial cells. Proceedings of the American Association of Cancer Research 1999; 39:315.

  63. Mestre JR, Subbaramaiah K, Sacks PG, Schantz SP, Bhatia K, Jetten AM, Tanabe T, Inoue H, Dawson MI, Dannenberg AJ. Receptor-selective and anti-AP-1 selective retinoids suppress phorbol ester and epidermal growth factor-mediated induction of cyclooxygenase-2 (Cox-2). Proceedings of the American Association of Cancer Research 1999; 39:359.

  64. Liu J, Park JY, Schantz S, Kaur T, Stern J, Lazarus P. Influence of smoking and alcohol consumption of genotype-associated susceptibility to oral cancer. Proceedings of the American Association of Cancer Research. 1999; 39:627.

  65. Pitman MJ, Rosenthal JM, Yu G, McCormick S, Savage H, Schantz SP. Native cellular fluorescence of thyroid nodules. Otolaryngology Head and Neck Surgery 2003; 129: p106.

  66. Huang Q, Sacks P, McCormick S, Gutkind J, Mo J, Schantz SP. Molecular and cytogenetic analyses of an oral premalignant cell line during its malignant transformation. Proceedings of the American Association of Cancer Research. 2004.

  67. Reyes I, Iacob C, Chang Y, Suslina N, Policastro A, Moscatello A, Schantz S, Schaefer S, Tiwari R, Geliebter J. Idenitification of kallikrein 10 and frizzeled-related protein 2 as candidate molecular markers for papillary thyroid carcinoma using microarray analysis. Proceedings of the American Association of Cancer Research 2005; 46:9.

  68. Huang Q, GeliebterJ, Tiwari R, Yuan-Gen C, McCormick SA, Schaefer S, Schantz SP. Down regulation of SMARCA2 and CASP1 and up-regulation of premalignant cell line. Proceedings of the American Association of Cancer Research. 2005: 46:16.

  69. Huang Q, Geliebter J, Tiwari R, Yuan-Gen, Chen, McCormick S, Schaefer S, Schantz SP. Significant differences of genetic patterns between papillary thyroid carcinoma-derived and follicular carcinoma-derived cell lines detected by comparative genomic hybridization. Proceedings of the American Association of Cancer Research 2005; 46:31. 

  70. Tadi K, Chang Y, Schantz S, Schaefer S, Moscatello A, Geliebter J, Tiwari R. Reponsiveness of papillary cancer to estradiol: Clinical implications for prevention and therapy. Proceedings of the American Association of Cancer Research 2005; 46:371.

  71. Chen Y, Tadi K, Badithe T, Chang Y, Schantz S, Schaefer S, Moscatello A, Tiwari R. Akt signal transduction pathway is a target of diinolylmethane and indole -3-carbinol in thyroid cancer. Proceedings of the American Association of Cancer Research. 2005; 46:577.

  72. Ismael Reyes, Robert Suriano, Nina Suslina, Steve Schaefer, Stimson Schantz, Raj K. Tiwari, Jan Geliebter. Expression of proteins associated with extracellular matrix remodeling in papillary thyroid carcinoma representing potential clinical biomarkers. Proceedings of the American Association of Cancer Research. 2006

  73. Nicolas T. Kummer, Ismael Reyes, Codrin Iacob, Steve Schaefer, Stimson Schantz, Jan Geliebter. 5-Lipoxygenase and 15-Lipoxygenase-2 Expression in Papillary Thyroid Carcinoma; Potential Therapeutic Targets and Prognostic Markers. Proceedings of the American Association of Cancer Research. 2006

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