Clinical Trials in Ophthalmology - New York Eye & Ear Infirmary

Current Research
Clinical Trials in Ophthalmology

	Ophthalmology Research

	Otolaryngology Research

	Pathology & Laboratory Medicine Research

	Plastic & Reconstructive Surgery Research

	Institutional Review Board (IRB)

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Lab Technician at the Computer Since its founding in 1820, The New York Eye and Ear Infirmary mission has been for excellence in patient care for eye disease as well as education of eye care providers. To maintain excellence, research must be an integral part of this mission.

Researchers at The New York Eye and Ear Infirmary were among the first to use the laser in treating retinal diseases. Today, the Department of Ophthalmology maintains a strong commitment to medical research, which contribute to advances in Ophthalmology and related areas of medicine.

Research of medical practitioners is facilitated by a staff of research scientists, neuro-ophthalmolgists, pathologists, and electrophysiologists, who likewise conduct independent research in their respective areas.

The New York Eye and Ear Infirmary continues to be involved in many clinical and translational research projects. This site makes information about these trials available to all. The active protocols have information about:

the issue being studied and goal for the research
inclusion and exclusion criteria
contact person
other pertinent information

For results of previous studies, go to www.clinicaltrials.gov

Want more information about Ophthalmology Research?

	Bacterial Conjunctivitis (Pink Eye)
	Study/Title	Principal Investigator
	A Study to Evaluate the Clinical and Microbial Efficacy of 0.6% ISV-403 Compared to Vigamox™ in the Treatment of Bacterial Conjunctivitis	Lois McNally, MD
	Glaucoma
	Clinical Comparison of the Proview Eye Pressure Monitor with the Goldmann Applanation Tonometer	Jeffrey Liebmann, MD
	Plazma Homocysteine Levels in Exfoliation Syndrome With or Without Glaucoma	Roberto Vessani, MD
	Collection of Normal Values With the GDx Access	Jeffrey Liebmann, MD
	The International Collaborative Exfoliation Syndrome Treatment Study (ICEST)	Robert Ritch, MD
	Genetic Testing to Evaluate the Prevalence of Glaucoma Associate Genes in Exfoliative Glaucoma and Pigmentary Glaucoma Patients	Robert Ritch, MD
	Effect of Ginkgo Biloba Extract on Ocular Blood Flow in Glaucoma	Robert Ritch, MD
	Ultrasound Biomicroscopy in Primary Acute Angle Closure Glaucoma (AACG)	Robert Ritch, MD
	A One Year, Investigator-Masked, Prospective, Randomized, Naturalistic, Observational Study of the Safety and Efficacy of Lumigan, Xalatan and Travatan in the Management of Elevated IOP in Patients with Open-Angle Glaucoma and Ocular Hypertension	Paul Sidoti, MD
	Ocular Oncology
	The Collaborative Ocular Melanoma Study	Paul Finger, MD
	Ocular Trauma
	Trauma Registry
	Oculoplastic & Orbital Surgery
	Thyroid Eye Disease Study	Robert Della Rocca, MD Paul Latkany, MD
	Ophthalmology Safety
	A two year open label, randomized, parallel group, blinded assessment ophthalmologic safety study of pramipexole IR versus ropinirole in early Parkinson's Disease patients	Alessandra Bertolucci, MD
	Refractive Surgery
	LASIK for Hyperopia with Astigmatism	Barrie Soloway, MD
	LASIK for Surgically Induced Hyperopia with and without Astigmatism	Barrie Soloway, MD
	Large Optical Zone Treatment with LADAR Vision for night glare prevention after LASIK	Barrie Soloway, MD
	LASIK and Dry Eyes	Barrie Soloway, MD
	LASIK for Spherical Hyperopia	Barrie Soloway, MD
	Standardization of Glaucoma testing after LASIK	Barrie Soloway, MD
	SRP (Surgical Reversal of Presbyopia)	Barrie Soloway, MD
	Retina
	Retinal Imaging
	Comparison of OCT-Opthalmoscope and Standard OCT Technology Instrument For the Imaging of Macular Hole Pathology	Richard Rosen, MD
	Macular Pigment Density Measurements Using Auto Fluorescence HRA	Richard Rosen, MD
	Central Retinal Vein Occlusion (CRVO)
	The Standard Care vs. Corticosteroid for Retinal Vein Occlusion (SCORE) Study	Richard Rosen, MD Belinda Shirkey, MD
	Diabetic Macular Edema
	A 3-Year, Phase 3, Multicenter, Masked, Randomized, Sham-Controlled Trial to Assess the Safety and Efficacy of 700 µg and 350 µg Dexamethasone Posterior Segment Drug Delivery System (DEX PS DDS Applicator System) in the Treatment of Patients with Diabetic Macular Edema	Richard Rosen, MD
	Evaluation of Steroid Implant to Conventional Laser Treatment for the Treatment of Diabetic Macular Edema That Received Prior Macular Laser Treatment	Paul Latkany, MD
	Age Related Macular Degeneration
	The Age-Related Eye Disease Study II (AREDS II): A Multi-center, Randomized Trial of Lutein, Zeaxanthin, and Long-Chain Omega-3 Fatty Acids (Docosahexaenoic acid [DHA] and Eicosapentaenoic acid [EPA]) in Age-Related Macular Degeneration	Richard Rosen, MD
	A Phase IV, Open Label, Multi-Center, Trial of Maintenance Intravitreous Injections of Macugen® (Pegaptanib Sodium) Given Every 6 Weeks for 48 Weeks in Subjects with Subfoveal Neovascular Age-Related Macular Degeneration (AMD) Initially Treated with a Modality Resulting in Maculopathy Improvement, EOP 1023	Richard Rosen, MD
	New A Randomized, Double Masked, Active Controlled Phase III Study of the Efficacy, Safety, and Tolerability of Repeated Doses of Intravitreal VEGF Trap in Subjects with Neovascular Age-Related Macular Degeneration- (CLEAR IT 3)	Richard Rosen, MD
	New A Phase 3, randomized, double-masked, parallel-assignment study of intravitreal bevasiranib sodium, administered every 8 or 12 weeks as maintenance therapy following three injections of Lucentis® compared with Lucentis® monotherapy every 4 weeks in patients with Exudative Age-Related Macular Degeneration (AMD) - ACU301B	Richard Rosen, MD
	New Serial Retinal Thickness Changes and Scotoma Size Measured with Lucentis Therapy measured Using the OCT Ophthalmoscope (OCT/SLO)® and the Foresee Preferential Hyperacuity Perimeter TM PROTOCOL FVF4193s	Richard Rosen, MD
	New A Phase II Multicenter, Randomized, Double-Masked, Placebo-Controlled, Dose-Comparison Study of the Safety and Efficacy of Fenretinide in the Treatment of Geographic Atrophy in Subjects With Age-Related Macular Degeneration	Richard Rosen, MD
	Macular Telangiectasia
	A Natural History Study Of Macular Telangiectasia- The MacTel Study	Richard Rosen, MD
	Uveitis
	Steroid Implant for the Treatment of Posterior Uveitis	Paul Latkany, MD
	Uveitis Genetics	C. Michael Samson, MD
	An 8-Week, Multicenter, Masked, Randomized Trial (with an 18-Week Masked Extension) to Assess the Safety and Efficacy of 700 μg and 350 μg Dexamethasone Posterior Segment Drug Delivery System (DEX PS DDS) Applicator System Compared with Sham DEX PS DDS Applicator System in the Treatment of Non-Infectious Ocular Inflammation of the Posterior Segment in Patients with Intermediate Uveitis	C. Michael Samson, MD
	A 6-Week, Multicenter, Masked, Randomized Trial (with a 20-Week Masked Extension) to Assess the Safety and Efficacy of 700 μg and 350 μg Dexamethasone Posterior Segment Drug Delivery System (DEX PS DDS) Applicator System Compared with Sham DEX PS DDS Applicator System in the Treatment of Non-Infectious Ocular Inflammation of the Anterior Segment in Patients with Anterior Uveitis	C. Michael Samson, MD
	Multicenter Uveitis Steroid Treatment Trial (MUST)	Paul Latkany, MD
	The Use of Confocal Microscopy to Characterise Keratic Precipitates (KPs) in Sarcoidosis- Associated Uveitis	C. Michael Samson, MD Samir, Tari, MD
	Quantification of the Effect of Free Radicals in Sera and Tear Films of Uveitic Patients	C. Michael Samson, MD Samir, Tari, MD
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NYEE Eye Research Centers

Aborn Eye Research Center
Among this active research lab's discoveries is the invention of the first modern system of corneal topography, now manufactured commercially as the Topographic Modeling System (TMS).

Advanced Retinal Imaging Laboratory
This specialty facility explores new technologies for imaging the human retina in order to enhance our understanding of the anatomy, physiology and visual function.

Glaucoma Services
Clinical service at the forefront of innovation in diagnostic and therapeutic advances in the understanding and treatment of glaucoma.

Ocular Pathology Laboratory
A major referral center for the Metropolitan area and the Northeastern US.

The New York Glaucoma Institute
Created to support research into the basic causes of glaucoma, increase public awareness of glaucoma, and promulgate educational material for ophthalmologists, other physicians, and persons with glaucoma.

The Ocular Imaging Center
Ultrasound Biomicroscopy (UBM) and Optical Coherence Tomography (OCT) clinical databases.

New York Medical College
Additional research facilities are located amongst affiliated hospitals and universities of the academic department.

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