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What is New in Eye Research?Since its founding in 1820, The New York Eye and Ear Infirmary mission has been for excellence in patient care for eye disease as well as education of eye care providers. To maintain excellence, research must be an integral part of this mission.

Researchers at The New York Eye and Ear Infirmary were among the first to use the laser in treating retinal diseases. Today, the Department of Ophthalmology maintains a strong commitment to medical research, which contribute to advances in Ophthalmology and related areas of medicine.

Research of medical practitioners is facilitated by a staff of research scientists, neuro-ophthalmolgists, pathologists, and electrophysiologists, who likewise conduct independent research in their respective areas.

The New York Eye and Ear Infirmary continues to be involved in many clinical and translational research projects. This site makes information about these trials available to all. The active protocols have information about:

  • the issue being studied and goal for the research
  • inclusion and exclusion criteria
  • contact person
  • other pertinent information

Find current clinical trials in Ophthalmology

For results of previous studies, go to www.clinicaltrials.gov

Glaucoma

Study/Title

Principal Investigator

Non-Invasive, Non-Contact Imaging of the Anterior Segment by Anterior Segment OCT

Robert Ritch, MD

Anterior segment imaging using ultrasound biomicroscopy (UBM) and slit lamp optic coherence tomography (SL-OCT) in patients using alpha-adrenergic blockers.

Robert Ritch, MD

In Vivo Three Dimensional Confocal Laser Scanning Microscopy of Anterior Segment Structures Using the HRT II Rostock Cornea Module

Robert Ritch, MD

Unilateral exfoliative glaucoma: comparing functional tests using short-wavelength automated perimetry, frequency doubling technology perimetry and multifocal visual evoked potential

Robert Ritch, MD

Evaluation of patients with normal-tension glaucoma (NTG) or high-tension glaucoma (HTG) using different visual field studies and nerve fiber layer imaging

Robert Ritch, MD

A Multi-center, double-masked, randomized, placebo-controlled, ascending dose study of INS115644 ophthalmic solution in subjects with bilateral ocular hypertension or early open angle glaucoma.

Robert Ritch, MD

Functional and Structural Testing for Optic Nerve Disease

Robert Ritch, MD

Randomized, Controlled, Multicenter Comparative Trial to Evaluate for the SOLX Gold Shunt for the Reduction of Intraocular Pressure (IOP) In Glaucomatous Eyes Following Failed Medical and Conventional Surgical Treatments

Robert Ritch, MD

Ocular Oncology

The Collaborative Ocular Melanoma Study

Paul Finger, MD

Ocular Trauma

Trauma Registry

 

Oculoplastic & Orbital Surgery

Thyroid Eye Disease Study

Robert Della Rocca, MD
Paul Latkany, MD

Refractive Surgery

SRP (Surgical Reversal of Presbyopia)

Barrie Soloway, MD

Retina

Retinal Imaging

Comparison of OCT-Opthalmoscope and Standard OCT Technology Instrument For the Imaging of Macular Hole Pathology

Richard Rosen, MD

Macular Pigment Density Measurements Using Auto Fluorescence HRA

Richard Rosen, MD

Diabetic Macular Edema

A 3-Year, Phase 3, Multicenter, Masked, Randomized, Sham-Controlled Trial to Assess the Safety and Efficacy of 700 µg and 350 µg Dexamethasone Posterior Segment Drug Delivery System (DEX PS DDS Applicator System) in the Treatment of Patients with Diabetic Macular Edema

Richard Rosen, MD

Age Related Macular Degeneration

A Randomized, Double Masked, Active Controlled Phase III Study of the Efficacy, Safety, and Tolerability of Repeated Doses of Intravitreal VEGF Trap in Subjects with Neovascular Age-Related Macular Degeneration- (CLEAR IT 3)

Richard Rosen, MD

A Phase 3, randomized, double-masked, parallel-assignment study of intravitreal bevasiranib sodium, administered every 8 or 12 weeks as maintenance therapy following three injections of Lucentis® compared with Lucentis® monotherapy every 4 weeks in patients with Exudative Age-Related Macular Degeneration (AMD) - ACU301B

Richard Rosen, MD

Serial Retinal Thickness Changes and Scotoma Size Measured with Lucentis Therapy measured Using the OCT Ophthalmoscope (OCT/SLO)® and the Foresee Preferential Hyperacuity Perimeter TM PROTOCOL FVF4193s

Richard Rosen, MD

A Genetic Study of Macular Degeneration

Richard Rosen, MD

Macular Telangiectasia

A Natural History Study Of Macular Telangiectasia- The MacTel Study

Richard Rosen, MD

Uveitis

Uveitis Genetics

C. Michael Samson, MD

Multicenter Uveitis Steroid Treatment Trial (MUST)

Paul Latkany, MD

The Use of Confocal Microscopy to Characterise Keratic Precipitates (KPs) in Sarcoidosis- Associated Uveitis

C. Michael Samson, MD
Samir, Tari, MD

Quantification of the Effect of Free Radicals in Sera and Tear Films of Uveitic Patients

C. Michael Samson, MD
Samir, Tari, MD

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Want more information about Ophthalmology Research?

NYEE Eye Research Centers

Advanced Retinal Imaging Laboratory
This specialty facility explores new technologies for imaging the human retina in order to enhance our understanding of the anatomy, physiology and visual function.

Glaucoma Services
Clinical service at the forefront of innovation in diagnostic and therapeutic advances in the understanding and treatment of glaucoma.

Ocular Pathology Laboratory
A major referral center for the Metropolitan area and the Northeastern US.

The New York Glaucoma Institute
Created to support research into the basic causes of glaucoma, increase public awareness of glaucoma, and promulgate educational material for ophthalmologists, other physicians, and persons with glaucoma.

The Ocular Imaging Center
Ultrasound Biomicroscopy (UBM) and Optical Coherence Tomography (OCT) clinical databases.

New York Medical College
Additional research facilities are located amongst affiliated hospitals and universities of the academic department.

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